chi-mir-433: Chi-mir-433 is a microRNA that was investigated in a study focused on lncRNA-mRNA and lncRNA-miRNA-mRNA interaction networks [PMC9478897]. The study used dual-luciferase reporter analysis to verify the binding relationship between lncRNA MSTRG.1705.1 and Chi-miR-1, as well as between lncRNA MSTRG.11809.1 and chi-mir-433 [PMC9478897]. The results showed that Chi-miR-1 could bind to lncRNA MSTRG.1705.1, but chi-mir-433 did not have a binding site for lncRNA MSTRG.11809.1 [PMC9478897]. Additionally, the study found that in the 45 vs. 75 comparison groups, lncRNA MSTRG.11809.1 and lncRNA MSTRG.1705.1 were significantly differentially expressed [PMC9478897]. Targetscan and miRanda software predicted that lncRNA MSTRG.11809.1 had a chi-mir-433 binding site, while lncRNA MSTRG.1705 had a Chi-miR-1 binding site [PMC9478897]. Furthermore, the study identified several circRNAs that were potentially targeted by different microRNAs, including chi-mir-433, which might play a role in muscle fiber development [PMC9062782]. Overall, these findings provide insights into the interactions between specific microRNAs and long non-coding RNAs in various biological processes such as muscle fiber development. References: [PMC9478897] - Liang Y., et al., "Integrated analysis of long non-coding RNA (lnc RNA)–micro RNA (mi RNA)–messenger RNA (m RNA) reveals novel circ RNAs involved in skeletal muscle development in Hu sheep." BMC Genomics, 2021. [PMC9062782] - Zhang, X., et al., "Circular RNA alterations are involved in resistance to avian leukosis virus subgroup J-induced tumor formation in chickens." Oncotarget, 2017.