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gga-mir-125b: Gga-mir-125b is a specific type of microRNA that has been studied in relation to tumorigenesis and viral infections. Real-time PCR was used to analyze the expression of gga-mir-125b in ALV-J-infected chickens, and it was found to be differentially expressed [PMC6723722]. In addition, gga-mir-125b was shown to be associated with tumorigenesis-related pathways and ALV-J-induced tumorigenesis [PMC5065965]. Several other miRNAs, including gga-mir-125b, have also been reported to be associated with tumorigenesis and viral infections [PMC5276853]. Furthermore, gga-mir-125b displayed opposing expression patterns in infected liver tissues and dendritic cells [PMC7587795]. In the context of H5N1-infected chickens, gga-mir-125b was found to be down-regulated [PMC7931527]. The expression of gga-mir-125b has also been studied in relation to the MAPK signaling pathway and the Wnt signaling pathway in hepatic tumor tissues of chickens infected with ALV-J [PMC6862082]. Additionally, qRT-PCR analysis confirmed the differential expression of gga-miR-221, gga-miR-211, gga-miR-222a, gga-miR-193b, and gga-mir-125b in infected cells compared with mock-infected cells [PMC4735322]. Overall, these studies highlight the importance of understanding the role of miRNAs like gga-mir-125b in tumorigenesis and viral infections.
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