hsa-mir-656: Hsa-mir-656 is a microRNA that has been studied in various contexts. It has been obtained from Dharmacon and used in experiments involving co-transfection with other microRNA mimics and inhibitors [PMC3486798]. However, when hsa-mir-656 or hsa-miR-877-5p were transfected, there was no change in luciferase activity [PMC3486798]. It was initially anticipated that hsa-mir-656 would only interact with the CBR1 3'-UTR in its rs9024 polymorphic state, but no binding capacity was observed [PMC3486798]. Bioinformatic predictions identified hsa-mir-656 as a potential candidate for interacting with the 3'-UTR of CBR1, but it had no effect on CBR1 expression or activity [PMC3486798]. Hsa-mir-656 has also been predicted to target multiple genes, including EPS15 [PMC4838358]. In glioma, hsa-mir-656 expression levels are downregulated and it inhibits neurosphere formation and cell proliferation by targeting BMPR1A [PMC5260001]. Hsa-mir-656 has also been found to play a potential role in GBM progression [PMC5260001]. Additionally, changes in expression patterns of hsa-miR-92b, hsa-miR-137, hsa-mir-656, and other miRNAs were observed after exposure to low and high doses of X-ray radiation [PMC3424689]. Hsa-mir-656 is part of an imprinted DLK-DIO3 region that comprises multiple miRNA genes [PMC3563971].