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hsa-mir-4484: Hsa-mir-4484 is a microRNA that has been studied in various contexts. It has been found to be upregulated in patients with ONIHL (Occupational Noise-Induced Hearing Loss) [PMC5769754]. It has also been identified as one of the most expressed miRNAs in extracellular vesicles [PMC7062641]. In a study on patients with systemic sclerosis (SSc), hsa-mir-4484 demonstrated the highest upregulation compared to healthy subjects [PMC6776520]. Bioinformatics analysis has identified potential target genes of hsa-mir-4484 that may be related to the pathology of SSc [PMC6776520]. Hsa-mir-4484 has also been found to be upregulated in saliva samples from patients with malignant pleural effusion (MPE) compared to other groups [PMC7481620]. In addition, hsa-mir-4484 is one of four microRNAs that aligns to the mitochondrial genome at specific positions [PMC3439422]. The diagnostic value of hsa-mir-4484, along with another microRNA, hsa-miR-3663-3p, has been evaluated for distinguishing MPE patients from other groups [PMC7481620]. The expression levels of hsa-mir-4484 and hsa-miR-3663-3p have also been correlated with overall survival in lung squamous cell carcinoma patients [PMC7481620]. These findings suggest that hsa-mir-4484 may have potential as a diagnostic and prognostic biomarker in various diseases.
Genome locations
Gene Ontology annotations
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Localisation
Sequence
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