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Homo sapiens (human) long intergenic non-protein coding RNA 1419 (LINC01419) URS00001A8BAE_9606

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LINC01419: LINC01419 potentially suppresses RECK expression epigenetically via EZH2, promoting hepatocellular carcinoma (HCC) progression [PMC7346057]. Upregulation of LINC01419 has been observed in both lung adenocarcinoma (LUAD) and LUAD-cancer stem cells (CSCs) [PMC9438337]. Mass spectrometry analysis revealed a direct binding between LINC01419 and XRCC5 (Ku80), a protein involved in DNA damage repair in various cancers [PMC9325340]. In osteosarcoma (OS), the carcinogenic role of LINC01419 was confirmed through the LINC01419/miR-519a-3p/PDRG1 axis [PMC7201774]. Other lncRNAs, such as XIST, TINCR, MEG3, FENDRR, ADAMTS9-AS2, JHDM1D-AS1, MIR205HG, MBNL1-AS1, and PART1, have also been implicated in different types of cancer [PMC7550980].

Targeting miRNAs 7 total

According to LncBase, this RNA is targeted by the following miRNAs:

Genome locations

Gene Ontology annotations

Sequence

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CUUCCACAUCGUGGAAGCUUUGUUCUUUCGCUCUUUGCAAUAAAUCUUGCUACUGCUCACUCUUUGGGUCCACGCUGCUUUUAUGAGCUGUAACACUCACCGCGAAGAUCUGCAGCUUCACUCCCGAGCCAGCGAGACCACGAACCCACCAGAAGGAAGAAACUCCGAACACAUCUGAACAUCAGAAGGGCAGACUCCAGACACGCCACCUUAAGAGCUGUAACACUCACCGCGAGGGUCCACGGCUUCAUUCUUGAAGUCAGUGAGACCAAGAACCCACCAAUUCCGGACACAAUUUCUUGGCUCUCAGUGGCUUCCAUGGAAGUUCUGCAAUCAACCAGCAGGAGAACCGCUUAAACCCAGGAGGCGGAGGUUGCAGUGAGCCAAGUAUGCAUCACUGCACUCCAGCCUGGAAGACAGAGUGAGACCCUGUCUCAACAAAAUAAAUUAAAAUAAAAAAUAAUAUAUUUUUCUAACUAUCAUCCCUUUUCCAAAUCAGGAAUUCCCCUUAAGUUUUCCUCAAUUUCCAUGGCAAUAUCUUUGCAUAGAUUCAUUAAGAAUUUGUCCUUUUUAAAUAAAAAAUAUAAAGGGAACUAUUCAUUAGGCAACAAAUGCCUUGUCUGAAAUAUCACAUUUGAGAAUGCUGCUCAUUUAAUCAGAAAGGUACGCUACUUUAAAGAACUGAGGUCCACUUUCUGGAGCCAAAAACUCAUAAAUCCCUCUCAGAAAAACCUGAUUUGCUUUGUAGGGUCUCAGGUUUAGAGAUGCUGAAAAAGAUAUUUUCGUUGCAGACAAAGGACCUCAGAGUAUUUGGAGAACUUUGAGAAGAGAGGAAUUCUCCCAAAUGUAUAGGUGUCACAGGUAAAAUACAGUCGAGAGAUUUUCUUGGACUUUAAUUCCUUAAAUCAGGAUAGCAAAUAAUAGGGGCUUUUACAAAUUCAAUCUGUUUCCUUACAAAAAUUUUCAGCAAAGUAAUUUCAGCAAAUUAAUUUUCAGCAAAGUAAAUGUAAGAAGACUUAUGUGAAAAAUUAACAUUCUCCAUGUAUCUAUGAAGCCAAACCUAAUAAAACCAGCUUUAAUUUGUGCUCAAGAAUAUUAUUUCACUGAGUUUUCUUAAAUCACAAAGGGGAGACUGUUAUGAAAACUGAUAUAAAAUAAAAAAAACAAGGAAGAAAAGUCUACUAGAUGUCUCUAAUGGAAGACUGCAUUUUUAGAACAUAUCCUUAUAGGCGAUUCUAGCCUUUCUCUGCUAUUUGGCUCUCACACUCUUUACCGUGCAGAUAAUUCACAGCAAUGCAAAAGAAUCCUCAUCUAUAGCCAUGAAAAUAAGUUAUUUGUUAUUUCUGGUAAAGGUUCAAUUGACCUCCCCUUCCAGGAUGAAGAAAGUUUCAUGUCUUUCUGCAUCAUUUCAACUAUUCCUUACUACAUAUAAAUCUGCACUUGUUAACUUCUAUUUUGAAUUGAUUGUGGCAUCUGCCUGCUUCCCCAUUAAAACUGAAUAAAAUCUUUAACACAUAAAAA

Taxonomic tree

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Expression New Publications