cfa-mir-200c: Cfa-mir-200c is a microRNA that is part of the miR-200 family and is transcribed from chromosome 27 [PMC4049822]. In a study on the epididymis of dogs, it was found that the expression of cfa-mir-200c was increased in dogs older than 3 years of age [PMC10135127]. Along with cfa-mir-200c, other miRNAs such as cfa-miR-26a and members of the cfa-let-7 family were also found to have increased expression in older dogs [PMC10135127]. These miRNAs, including cfa-mir-200c, were shown to be involved in aging in dogs through their regulation via PTEN [PMC10135127]. In another study on spermatogenesis, it was found that exogenous administration of retinoic acid (RA) and a CYP26B1 inhibitor up-regulated the expressions of cfa-miR-200a, cfa-miR-200b, cfa-mir-200c, and cfa-miR-141 [PMC4049822]. These miRNAs were part of miRNA families such as miR-200 and Mirlet-7 that were significantly up-regulated with testicular RA intervention [PMC4049822]. Additionally, other miRNAs such as cfa-miR18a, cfa-miR20b, and cfa-miR21 were also identified in this study [PMC9032658]. Overall, these findings highlight the involvement of cfa-mir-200c in aging and spermatogenesis processes in dogs.