mmu-mir-23b: Mmu-mir-23b is a microRNA that plays a role in various biological processes. It is involved in the differentiation of primordial germ cells by regulating the Lin28 and Blimp1 genes [PMC9505168]. Mmu-mir-23b is also identified as a differentially expressed microRNA (DEmiRNA) in both neural stem/progenitor cell (NSPC)-induced endothelial cell (EC) alteration and EC-induced NSPC alteration [PMC7758130]. However, its expression patterns differ in these situations [PMC7758130]. Mmu-mir-23b, along with mmu-miR-23a and mmu-miR-210, has been found to be involved in the crosstalk between ECs and NSPCs [PMC7758130]. It has also been implicated as critical for maintaining the glomerular filtration barrier [PMC2658734]. In a study on diet-induced obesity, mmu-mir-23b was found to be downregulated in obese mice compared to lean mice [PMC4571067]. In mice primordial germ cells (PGCs), exposure to vinclozolin during pregnancy led to a decrease in mmu-mir-23b expression, which downregulated the Lin28/let-7/Blimp1 PGC specification pathway across three generations [PMC9563050]. Mmu-mir-23b has a predicted binding site on the 3' untranslated region (3'UTR) of Runx2 mRNA at position 1002–1008 [PMC4768947]. Overall, mmu-mir-23b is involved in germ cell differentiation, crosstalk between ECs and NSPCs, glomerular filtration barrier maintenance, obesity-related miRNA dysregulation, PGC specification pathway regulation by environmental exposure, and potential regulation of Runx2 mRNA [PMC9505168][PMC7758130][PMC2658734][PMC4571067][PMC9563050][PMC4768947].