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hsa-miR-3198: Hsa-mir-3198 is a microRNA that has been studied in various contexts. In one study, it was found that QPCR resulted in multiple products for several candidates, including hsa-mir-3198, making it difficult to determine their overexpression in the ovary [PMC5223123]. However, other studies have identified hsa-mir-3198 as one of the most significantly differentially expressed miRNAs. It has been found to be downregulated in saliva samples [PMC8742548]. Hsa-mir-3198 has also been implicated in hepatocellular carcinoma recurrence, epithelial ovarian cancer, metastatic colorectal cancer, and inhibition of nasopharyngeal carcinoma proliferation [PMC8742548]. In a study on the effects of cigarette smoking on miRNA expression, hsa-mir-3198 was found to be downregulated in nicotine-treated periodontal ligament stem cells (PDLSC) [PMC5379007]. However, its expression trend was opposite to that observed in smoker PDLSCs with reduced regenerative potential [PMC5379007]. Hsa-mir-3198 has also been identified as one of the "low-5" miRNAs with low activation scores among all human miRNAs [PMC8677043]. Additionally, it has been shown to interact with several other miRNAs and mRNAs [PMC9428625]. Overall, hsa-mir-3198 is a microRNA that exhibits differential expression and potential functional roles in various biological processes and diseases.
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