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mmu-mir-146a: Sequencing analysis showed that the genome editing activities were confirmed at a rate of 8.2% (4 mutated sequences out of 48 sequences) for mmu-mir-146a [PMC3797721]. Mmu-mir-146a levels were measured in adipocyte and SVF fractions using miRCURY LNA RT PCR [PMC6395003]. Mmu-mir-146a is one of the up-regulated miRNAs in HFD-induced obesity [PMC3319598]. It was found to bind to the 3'UTR region of 14 potential target genes [PMC8293491]. Mmu-mir-146a was also associated with immune-related signaling molecules Traf6 and Irak1 and showed upregulation upon CS exposure [PMC7218232]. Additionally, it was marginally significantly associated with postoperative cognitive dysfunction (POCD) [PMC6704709]. A specific sequence for mmu-mir-146a (5′-CUGAGAACUGAAUUCCAUGGGUUAUAUCAAUGUCA-3′) was purchased for experimentation purposes [PMC4346627].
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