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mmu-mir-294: Mmu-mir-294 is a miRNA mimic that was transfected in a study described in [PMC2958809]. It is part of the mmu-miR-290-295 cluster, which has been shown to play a role in pluripotency regulation [PMC9149258]. In various experiments, mmu-mir-294 was found to be highly expressed, along with other miRNAs from the cluster [PMC3287988]. Mmu-mir-294 has been shown to promote pluripotency by regulating c-Myc target genes and upregulating pluripotency-associated genes such as Lin 28 [PMC9149258]. It has also been implicated in the post-transcriptional regulation of Cdkn1a [PMC9149258]. Detection of mmu-mir-294 can be improved using EDC cross-linking compared to UV cross-linking [PMC1885651]. Mmu-mir-294 is predicted to target the activin receptor 1 (ACVR1) gene, along with other miRNAs from the cluster [PMC4499447]. It belongs to the AAGUGCU seed family, which includes other miRNAs such as mmu-miR-291a-3p and mmu-miR-295 [PMC4132708].
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