Hsa-Mir-642: Hsa-mir-642 is a specific microRNA that is present in extracellular vesicles (EVs) derived from activated NCFs and has been linked to breast cancer [PMC7381355] [PMC7929672]. It is also an adipocyte-specific microRNA and may be associated with metabolic parameters such as Body Mass Index, blood cholesterol and fatty acids levels, and insulin resistance [PMC3945012]. Analysis of hsa-mir-642 in a population of 100 healthy subjects revealed two distinct groups with high or low/undetectable levels of hsa-mir-642 [PMC3945012]. Gender-driven differences showed higher expression of hsa-miR-10b and hsa-mir-642 in males compared to females [PMC3945012]. Various assays, inhibitors, and probes have been used to study hsa-mir-642 in different contexts [PMC3473298] [PMC8533892] [PMC5042920]. Hsa-mir-642 has also been found to be differentially expressed in pancreatic neuroendocrine tumors (PNETs) compared to pancreatic ductal adenocarcinomas (PDACs) [PMC7352720]. In osteosarcoma patients, high expression of hsa-mir-642 is associated with poor prognosis, while low expression is also linked to poor prognosis for other miRNAs [PMC9553349]. Hsa-mir-642 has been identified as one of the microRNAs that show significant correlations with viral load, suggesting its potential as a biomarker for infection status [PMC8066103]. References: [PMC7381355] [PMC7929672] [PMC3945012] [PMC3473298] [PM8533892] [PM5042920] [PM7352720] [PM9553349] [PM8066103]