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cfa-mir-223: In a study on chronic lymphocytic leukemia (CLL), the expression pattern of 12 canine miRNAs, including cfa-mir-223, was analyzed [PMC3619122]. Four of these miRNAs, including cfa-mir-223, were found to have stable expression and were used as endogenous controls [PMC3619122]. Other miRNAs, such as cfa-miR-382, cfa-miR-380, cfa-miR-199, and cfa-miR-21 (including its less abundant product cfa-miR-21*), were found to be positively associated with plasma PIIINP concentration [PMC3668254]. Cfa-mir-223 was also positively associated with plasma PIIINP concentration but showed a significant elevation only from day 14 [PMC3668254]. CmiRNA panel selection included cfa-mir-223 due to its stability in serum [PMC9951723]. Cfa-mir-223 was used as a control in one study but was found to be inappropriate for normalization of RT-qPCR data in the context of infection [PMC4102413].
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