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cfa-mir-26b: Cfa-mir-26b is a canine microRNA that has been studied in various contexts. In a study analyzing the expression pattern of 12 canine miRNAs in chronic lymphocytic leukemia (CLL), cfa-mir-26b was one of the four miRNAs used as endogenous controls due to its stable expression [PMC3619122]. Additionally, cfa-mir-26b was selected for validation in microarray results in CLL [PMC5678797]. In adrenal cortex samples, cfa-mir-26b was part of the miRNA families with high abundance, including cfa-miR-30 and cfa-miR-7 families [PMC4768678]. In metastatic and non-metastatic mammary tumors, cfa-mir-26b showed significant differential expression [PMC7646326]. However, its expression levels were relatively low compared to other miRNAs across various cell lines [PMC8379617]. Furthermore, in veterinary patients with congestive heart failure (CHF), downregulation of cfa-mir-26b was observed in canine ventricular and atrial muscles after CHF development subsequent to experimental ventricular pacing [PMC5533140]. Overall, these studies highlight the involvement of cfa-mir-26b in different biological processes and its potential as a biomarker or therapeutic target.
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