cfa-mir-193b: Cfa-mir-193b is a miRNA that is ubiquitously expressed in dogs, including the liver [PMC4989286]. In dogs with liver injury, the serum levels of cfa-mir-193b were elevated [PMC4989286]. Serum analysis also revealed the presence of other miRNA biomarkers for various tissues, such as cfa-miR-122 and -885 for the liver, cfa-miR-1, -133, and -206 for the heart/muscle, miR-34b/c for the testis, cfa-miR-216 for the pancreas, and cfa-miR-212 for the brain [PMC4989286]. The up-regulation of cfa-mir-193b in response to T. canis infection may enhance the host immune response and contribute to host resistance against infection [PMC9773451]. At 24 hours post-infection (hpi), four differentially expressed miRNAs were identified as potential regulators of 48 target genes. Among them were cfa-miR-122 and cfa-mir-193b [PMC9773451]. In this study, cd22 was predicted as a potential target gene for cfa-mir-193b [PMC9773451]. Additionally, other miRNAs such as novel_328 and cfa-miR-331 were found to be associated with host immune response [PMC9773451]. Overall, these findings suggest that elevated levels of cfa-mir-193b may play a role in regulating immune responses and potential target genes in dogs with liver injury or T. canis infection.