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Capra hircus (goat) chi-miR-135a URS00000DF6D0_9925

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chi-mir-135a: Chi-mir-135a is a miRNA that binds to XR_311113.2 via putative binding sites, along with three other miRNAs (chi-miR-424-5p, chi-miR-544-5p, and chi-miR-3955-5p) [PMC8762113]. Mutants of chi-mir-135a, chi-miR-424-5p, and chi-miR-544-5p were transfected into GK cells to confirm their binding to XR_311113.2 [PMC8762113]. The miRNA binding site regions and mutated regions of chi-mir-135a were cloned into pmirGLO vectors for further analysis [PMC8762113]. XR_311113.2 contains binding sites for all four miRNAs (chi-mir-135a, chi-miR-424-5p, chi-miR544-p, and chi-miR3955-p) [PMC8762113]. Chi-mir135a is also down-regulated in three prenatal stages and the neonatal stage [PMC5087842]. Additionally, there are 17 down-regulated miRNAs that are common between these stages including Chi mir 135a [PMC5087842]. These findings suggest that Chi mir 135a may play a role in prenatal development and neonatal stage regulation along with other down-regulated miRNAs [PMC5087842].

Genome locations

Gene Ontology annotations

Sequence

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UAUGGCUUUUUAUUCCUAUGUGA

Taxonomic tree

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This sequence is found in 51 other species

  1. Alligator mississippiensis (American alligator) Ami-Mir-135-P2_5p (mature (guide))
  2. Anolis carolinensis (green anole) aca-miR-135-5p
  3. Ateles geoffroyi (black-handed spider monkey) age-miR-135
  4. Bos taurus (cattle) bta-miR-135a
  5. Callithrix jacchus (white-tufted-ear marmoset) cja-miR-135
  6. Callorhinchus milii (elephant shark) Cmi-Mir-135-P2_5p (mature (guide))
  7. Canis lupus familiaris (dog) cfa-miR-135a-5p
  8. Cavia porcellus (domestic guinea pig) cpo-miR-135a-5p
  9. Chrysemys picta bellii (western painted turtle) Cpi-Mir-135-P2_5p (mature (guide))
  10. Columba livia cli-miR-135-5p
  11. Danio rerio dre-miR-135a
  12. Dasypus novemcinctus (nine-banded armadillo) dno-miR-135a-5p
  13. Echinops telfairi (small Madagascar hedgehog) Ete-Mir-135-P2_5p (mature (guide))
  14. Eptatretus burgeri Ebu-Mir-135-P10_5p (mature (guide))
  15. Equus caballus eca-miR-135a
  16. Gadus morhua (Atlantic cod) Gmo-Mir-135-P2a_5p (mature (guide))
  17. Gallus gallus gga-miR-135a-5p
  18. Gekko japonicus Gja-Mir-135-P2_5p (mature (guide))
  19. Gorilla gorilla gorilla ggo-miR-135a (MIR135A)
  20. Gorilla gorilla (western gorilla) ggo-miR-135a
  21. Haplochromis burtoni (Burton's mouthbrooder) abu-miR-135c-5p
  22. Homo sapiens hsa-miR-135a-5p
  23. Ictalurus punctatus ipu-miR-135a
  24. Lagothrix lagotricha (brown woolly monkey) lla-miR-135
  25. Latimeria chalumnae Lch-Mir-135-P2_5p (mature (guide))
  26. Macaca mulatta mml-miR-135a-5p
  27. Maylandia zebra mze-miR-135c
  28. Microcaecilia unicolor Mun-Mir-135-P2_5p (mature (guide))
  29. Monodelphis domestica (gray short-tailed opossum) mdo-miR-135a-5p
  30. Monopterus albus Mal-Mir-135-P2a_5p (mature (guide))
  31. Mus musculus (house mouse) mmu-miR-135a-5p
  32. Neolamprologus brichardi (lyretail cichlid) nbr-miR-135c-5p
  33. Ophiophagus hannah (king cobra) oha-miR-135-5p
  34. Oreochromis niloticus (Nile tilapia) oni-miR-135c
  35. Ornithorhynchus anatinus oan-miR-135b-5p
  36. Oryctolagus cuniculus (rabbit) ocu-miR-135a-5p
  37. Pan paniscus ppa-miR-135
  38. Pan troglodytes ptr-miR-135a
  39. Petromyzon marinus pma-miR-135a-5p
  40. Pongo pygmaeus (Bornean orangutan) ppy-miR-135a
  41. Pundamilia nyererei pny-miR-135c-5p
  42. Python bivittatus pbv-miR-135-5p
  43. Rattus norvegicus rno-miR-135a-5p
  44. Sarcophilus harrisii (Tasmanian devil) Sha-Mir-135-P2_5p (mature (guide))
  45. Scyliorhinus torazame (cloudy catshark) Sto-Mir-135-P2_5p (mature (guide))
  46. Sphenodon punctatus Spt-Mir-135-P2_5p (mature (guide))
  47. Sus scrofa (pig) ssc-miR-135
  48. Taeniopygia guttata (zebra finch) tgu-miR-135a-5p
  49. Tupaia chinensis tch-miR-135a-5p
  50. Xenopus laevis Xla-Mir-135-P2d_5p (mature (co-guide))
  51. Xenopus tropicalis xtr-miR-135
Publications