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mmu-mir-706: Mmu-mir-706 is a type of microRNA that has been studied in various contexts. It has been found to closely match with Homo sapiens uncharacterized LOC105372576 [PMC6947010]. In experiments with MEL and MPRO cells, the 2'-O-methylated miRIDIAN mmu-mir-706 hairpin inhibitor was used to inhibit the activity of mmu-mir-706 [PMC4046156]. It is believed that Wfs1 and Dtl can regulate the expression of mmu-mir-706, along with other miRNAs [PMC7863986]. Mmu-mir-706 has been found to have a high degree of similarity with human hs-miR-6510-3p and is involved in alternative RNA splicing [PMC5387049]. In studies involving mice, the expression levels of mmu-miR-466 and mmu-mir-706 were significantly decreased [PMC3767082]. Mmu-mir-706 has also been found to be differentially expressed in various conditions, such as hepatic schistosomiasis and Star expression regulation [PMC9218868] [PMC3148237]. It targets mesodermal genes as well as Bcl2 modifying factor (Bmf) and vascular endothelial growth factor A (Vegfa) [PMC8509654]. The level of mmu-mir-706 was observed to be inversely related to that of its target gene Caspase-3 in mice infected with S. japonicum at 25 dpi [PMC4391475].
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