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Homo sapiens (human) hsa-miR-3136-5p URS00000AF45F_9606

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hsa-mir-3136: Hsa-mir-3136 is a microRNA that negatively regulates GNAQ and is involved in various diseases, including lung cancer, Klinefelter syndrome, childhood acute lymphoblastic leukemia, and breast cancer [PMC5548864] [PMC5548864]. In lung adenocarcinoma, hsa-mir-3136 and hsa-miR-3199-1 have relatively high correlation coefficients and contribute significantly to survival prediction [PMC5548864]. Hsa-mir-3136 is up-regulated in lung cancer compared to normal tissue [PMC5548864]. Additionally, a single nucleotide polymorphism occurs between hsa-mir-3136 and the 3' UTR of the lung cancer-related inflammatory gene KSR1 [PMC5548864]. Hsa-mir-3136 targets SOCS5 with down-regulation in lymphoblastoid cell lines, while hsa-miR-3199-1 targets CDK16 in 293 C cell lines [PMC5548864]. In a study ranking miRNAs, hsa-mir-3136 was among the top 10 miRNAs along with hsa-miR-3199-1 [PMC5548864].

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Gene Ontology annotations


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