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hsa-mir-548n: Hsa-mir-548n is a microRNA that has been identified as a candidate ID-miR for MCF7 cells and is significantly overrepresented in the targets of miRNA in MCF7 cells [PMC4401570]. Although hsa-mir-548n has been found to regulate many target genes, it has not been previously reported in sudden sensorineural hearing loss (SSNHL) [PMC5708990]. However, it is suggested that hsa-mir-548n, along with other miRNAs such as hsa-miR-34a, hsa-miR-15a, and hsa-miR-143, may have a role in the pathogenesis of SSNHL based on the role of their target genes in the disease [PMC5708990]. Hsa-mir-548n has also been found to be upregulated in patients with lymph node metastasis (LNM) in endometrial endometrioid carcinoma (EEC) [PMC8082502]. In breast cancer cells, dysregulated expression of hsa-mir-548n may be associated with the upregulation of lncRNA LINC01087 and may inhibit normal cell functioning by promoting proliferation [PMC6965516]. Hsa-mir-548n has also been associated with apoptotic pathways and tumor-suppression activity [PMC6965516]. In addition to hsa-mir-548n, another microRNA called hsa-miR-548ap-5p has also fulfilled stringent criteria for its potential role as a biomarker or therapeutic target [PMC4856985].
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