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gga-let-7i: Gga-let-7i is a downregulated miRNA that is associated with loss of tumor suppressive functions [PMC5065965]. It is involved in multiple signaling pathways, including MAPK, TGF-beta, Notch, Wnt, mTOR, Cell cycle, P53, and Jak-STAT [PMC9201442]. Through bioinformatic analysis and prediction analysis of the correlation between circRNA and miRNA, it was found that gga-let-7i can be targeted by multiple circRNAs [PMC9201442]. The expression of gga-let-7i has been detected in various studies [PMC3406056]. It has been reported that gga-let-7i is associated with tumorigenesis and the aberrant expression of the retrovirus ALV-J [PMC5276853].
In summary, gga-let-7i is a downregulated miRNA that plays a role in tumor suppression. It is involved in multiple signaling pathways and can be targeted by circRNAs. The expression of gga-let-7i has been detected in various studies. Furthermore, it has been reported to be associated with tumorigenesis and the aberrant expression of ALV-J retrovirus.
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