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hsa-mir-493: Hsa-mir-493 is a microRNA (miRNA) that has been identified as one of the 10 miRNAs with aberrant expression based on potential pathways of interest and/or chromosomal location [PMC3679163]. It is a pre-miRNA that encodes miRNAs at the 3p arm [PMC3303722]. Hsa-mir-493 has been found to interact with two hub genes simultaneously and has been reported in rheumatoid arthritis (RA) and ankylosing spondylitis (AS) [PMC9708466]. It has also been shown to have differential expression between multiple sclerosis (MS) patients experiencing a relapse and controls [PMC2708922]. Hsa-mir-493 is part of the chromosome 14 miRNA cluster (C14MC), and its expression decreases at the end of pregnancy [PMC4710532]. It is one of the hub differentially expressed (DE) miRNAs in breast cancer, with high expression associated with a better prognosis [PMC8722309]. Hsa-mir-493 has also been studied in relation to migration capacity, showing a negative correlation with migration capacity in certain contexts [PMC5433149]. Furthermore, it is involved in various cellular processes, including synaptic vesicle exocytosis, neurotransmitter receptor transport to plasma membrane, and glial cell projection [PMC9380744].
References:
[PMC3679163]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679163/
[PMC3303722]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303722/
[PMC9708466]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708466/
[PMC2708922]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708922/
[PM4710532]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710532/
[PMC8722309]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722309/
[PMC5433149]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433149/
[PMC9380744]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380744/
mRNA interactions
2 total
Genome locations
Gene Ontology annotations
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