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Homo sapiens (human) hsa-miR-1304-5p URS00000753AD_9606

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hsa-mir-1304: Hsa-mir-1304 is a microRNA that has been found to show a significant association in a median-nearby quantile, along with hsa-miR-137, hsa-miR-125b-2, and hsa-miR-26b [PMC7650743]. It has been identified in human embryonic stem cells and found to have one fixed substitution and one single nucleotide insertion [PMC3897851]. Overexpression of hsa-mir-1304 has been associated with the apoptotic characteristics of Bcl-xL in human lung adenocarcinoma cells [PMC8239963]. Hsa-mir-1304 is also part of ceRNA interactive axis genes associated with disease-free survival [PMC8457683]. It has been shown to be highly enriched in fatty acid biosynthesis and targets genes involved in fatty acid metabolism [PMC8148489][PMC8148489]. The rs2155248 G65T variant is located within hsa-mir-1304 [PMC6863982]. Hsa-mir-1304 has also been predicted to regulate differentially expressed genes associated with immune response and apoptotic signaling pathways [PMC5618721][PMC3858247][PMC3858247]. Additionally, it has been identified as a potential target gene for various diseases, including gastric cancer and breast cancer [PMC4359307][PMC7423976][PMC7423976][PMC7423976]. Hsa-mir-1304 is part of the hub ceRNA module associated with the PI3K/AKT signaling pathway [PMC7887822][PMC7887822]. It is also one of the differential miRNAs that have been screened for their involvement in liver hepatocellular carcinoma patients with low and high tumor mutational burden (TMB) [PMC7355149].

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Gene Ontology annotations


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