v24

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Homo sapiens (human) mitochondrially encoded tRNA-Met (AUA/G) (MT-TM) secondary structure diagram

Homo sapiens (human) mitochondrially encoded tRNA-Met (AUA/G) (MT-TM) URS000006E464_9606

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MT-TM: MT-TM is a mitochondrial gene that was found to be upregulated in a paediatric case, along with GDF15 and several other mitochondrial genes [PMC8803326]. This finding expands our understanding of the phenotypic spectrum of disease related to MT-TM mutations and the impact of pathogenic mt-tRNA gene variants in both paediatric and adult specialities [PMC6617384]. Additionally, CCL2 was found to be downregulated in the same case [PMC8803326]. This information suggests that MT-TM mutations may play a role in disease pathogenesis and highlights the importance of studying mitochondrial genes in various medical fields.

Genome locations

Gene Ontology annotations

Sequence

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AGUAAGGUCAGCUAAAUAAGCUAUCGGGCCCAUACCCCGAAAAUGUUGGUUAUACCCUUCCCGUACUA

Taxonomic tree

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This sequence is found in 29 other species

  1. Cloning vector pRS316-1B9 tRNA-Met
  2. Colobus guereza tRNA-Met
  3. Homo sapiens neanderthalensis neanderthalensis transfer RNA-Met
  4. Hylobates lar (common gibbon) transfer RNA-Met
  5. Hylobates muelleri tRNA-Met
  6. Pan paniscus mitochondrially encoded tRNA-Met (AUA/G) (ENSPPAG00000000009.1)
  7. Pan troglodytes tRNA-Met
  8. Pan troglodytes ellioti tRNA-Met
  9. Pan troglodytes schweinfurthii tRNA-Met
  10. Pan troglodytes troglodytes tRNA-Met
  11. Pan troglodytes ellioti tRNA-Met
  12. Pan troglodytes verus tRNA-Met
  13. Piliocolobus badius (western red colobus) tRNA-Met
  14. Plecotus auritus tRNA-Met
  15. Plecotus macrobullaris tRNA-Met
  16. Pongo abelii (Sumatran orangutan) tRNA (ENSPPYG00000020948.1)
  17. Presbytis sp. Pres2 tRNA-Met
  18. Pygathrix nemaeus (Red shanked douc langur) tRNA-Met
  19. Rhinopithecus bieti 1 RL-2012 tRNA-Met
  20. Rhinopithecus bieti 2 RL-2012 tRNA-Met
  21. Rhinopithecus bieti mitochondrially encoded tRNA-Met (AUA/G) (ENSRBIG00000000009.1)
  22. Trachypithecus barbei tRNA-Met
  23. Trachypithecus germaini (Indochinese lutung) tRNA-Met
  24. Trachypithecus hatinhensis tRNA-Met
  25. Trachypithecus laotum (Laotian langur) tRNA-Met
  26. Trachypithecus obscurus tRNA-Met
  27. Trachypithecus phayrei tRNA-Met
  28. Trachypithecus pileatus tRNA-Met
  29. Trachypithecus shortridgei (Shortridge's langur) tRNA-Met
 2D structure Publications