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Rattus norvegicus (Norway rat) rno-miR-495 URS000005A8ED_10116

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rno-mir-495: Rno-mir-495 is one of the twelve different types of miRNAs identified, including rno-miR-125b-5p, rno-miR-144-3p, rno-miR-24-3p, and novel-rno-miR-335-5p [PMC8529377]. In a study on fetal rats with anorectal malformations (ARMs), the expression of rno-mir-495 was found to be altered in the terminal hindgut [PMC6203938]. This miRNA is involved in feed-forward loops that amplify or inhibit the Fgf, Bmp, and Wnt signaling pathways implicated in the pathogenesis of ARMs [PMC6203938]. Additionally, several other miRNAs were also found to be altered in ARM fetal rats and involved in these signaling pathways [PMC6203938]. Among the predicted altered mRNAs associated with these miRNAs, Calml4 was found to correspond with six changed miRNAs including rno-mir-495 [PMC8529377]. Another mRNA, Acvr1c, corresponded with several other miRNAs including rno-mir-495 [PMC8529377]. In a study comparing different treatment groups for a liver-benefiting and rectifying decoction (LBRD), it was observed that rno-mir-495 was down-regulated in the LBRD treated group compared to the model group. This down-regulation predicted an up-regulation of target mRNAs such as GAT3, Calml4, Tnfaip6, Arc Gad1 and BDNF [PMC8529377].

mRNA interactions 8 total

Genome locations

Gene Ontology annotations


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This sequence is found in 17 other species

  1. Bos taurus bta-miR-495
  2. Callithrix jacchus cja-miR-495
  3. Canis lupus familiaris (dog) cfa-miR-495
  4. Capra hircus (goat) chi-miR-495-3p
  5. Cavia porcellus cpo-miR-495-3p
  6. Dasypus novemcinctus (nine-banded armadillo) dno-miR-495-3p
  7. Echinops telfairi Ete-Mir-154-P19_3p (mature (guide))
  8. Equus caballus (horse) eca-miR-495
  9. Homo sapiens hsa-miR-495-3p
  10. Macaca mulatta (Rhesus monkey) mml-miR-495-3p
  11. Mus musculus (house mouse) mmu-miR-495-3p
  12. Oryctolagus cuniculus (rabbit) ocu-miR-495-3p
  13. Ovis aries oar-miR-495-3p
  14. Pan troglodytes (chimpanzee) ptr-miR-495
  15. Pongo pygmaeus (Bornean orangutan) ppy-miR-495
  16. Pteropus alecto (black flying fox) pal-miR-495-3p
  17. Sus scrofa ssc-mir35