hsa-mir-141: Hsa-mir-141 is a microRNA that is found to be overexpressed in cisplatin resistant ovarian, gastric, and esophageal squamous cancer cells [PMC4682251]. In a study, gene expression levels of hsa-mir-141 were quantified using specific primers [PMC4981873]. The study used primers for hsa-mir-141 (#204504) and hsa-miR-200c (#2044852) from Exiqon [PMC4981873]. The overexpression of hsa-mir-141 in cisplatin resistant cancer cells suggests its potential role in drug resistance mechanisms [PMC4682251]. This microRNA may be involved in regulating gene expression and signaling pathways that contribute to resistance against cisplatin treatment [PMC4682251]. The quantification of gene expression levels using specific primers allows for the accurate measurement of hsa-mir-141 expression levels [PMC4981873]. This information can be valuable for understanding the mechanisms underlying drug resistance and developing targeted therapies to overcome it [PMC4981873]. Further research is needed to elucidate the specific targets and pathways regulated by hsa-mir-141 in cisplatin resistant cancer cells [PMC4682251]. Understanding the role of this microRNA can provide insights into potential therapeutic strategies for improving treatment outcomes in ovarian, gastric, and esophageal squamous cancers [PMC4682251].
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