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Homo sapiens (human) small nucleolar RNA host gene 3 (SNHG3) URS0000035204_9606

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SNHG3: SNHG3 is a long non-coding RNA (lncRNA) that has been implicated in various cancers, including bladder cancer, glioma, ovarian cancer, and prostate cancer. In bladder cancer, SNHG3 promotes the malignant phenotype of bladder cancer cells in vitro and inhibits the expression of GINS2, N-cadherin, and vimentin while upregulating E-cadherin expression in vivo [PMC7417716]. In glioma, SNHG3 is upregulated and associated with a poor prognosis. It promotes glioma cell progression by enhancing cell proliferation and suppressing apoptosis [PMC7747505]. In ovarian cancer, SNHG3 is involved in energy metabolism regulation and is associated with poor prognosis [PMC7640707]. In prostate cancer, SNHG3 is highly expressed in prostate cancer cell lines and its inhibition can suppress tumor progression [PMC7286463]. These findings suggest that SNHG3 may serve as a potential prognostic biomarker and therapeutic target for various cancers. However, the exact mechanisms by which SNHG3 exerts its effects are still not fully understood. Further research is needed to elucidate the specific interactions between SNHG3 and its target molecules in different types of cancers [PMC6827457][PMC7417716][PMC7640707][PMC7747505][PMC8805939][PMC9048787][PMC9260729].

Targeting miRNAs 96 total

According to LncBase, this RNA is targeted by the following miRNAs:

Genome locations

Gene Ontology annotations

Sequence

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AGACAUUCCAGGACUUCCGGGCACUUCGUAAGGUUUAAAAAGGAUGCUUCGCGUUUUCUCUCUCCUUUUUGGAGACAGAUUCGCAGUGGUCGCUUCUUCUCCUUGGAUUUGUUAAGGAUUCCAAGUAACUCUUAUUUGGAGAGAAGACGAUCUGCACUUCGCAUUUUGGCAUUGACAUUUAAUUUUAGGGUCCUUUAUAUAGAAGGGAGAGUAGGUAAACUGAUUUUUUUUUUUAACAGGGAGGGUUUGACAAUCUUUGGCAGACUUGGAGCAAAAGAUUGAGGUGCAUUUCAUGCCUCCUUUUGAGAGUCUUGCUCUGUCGCCCAGGCUGUAGUGCAGUGGCGCAAUCUUGGCUGCAACCUCAGCCUCCCAAGUAGCUGGGAUUACAAACAUAAGCCACCACGCCCAGCCCUCAUACCUCUUUUAAAAGUCGACCUGUUUUGCAGAAAGUCUGCUGUUUUUGUACUAAAGGCUUUGGAAUUUGGCAUUUAGCUAGGAAUGCACAUUCUUUCACCUCAUUCAUACUUUAAGAACCACAGAAGUGACUCUGCUUGGCCAGAAGGCACACUGUGUUGGUGGUUAUAUUAAAAGUCCUUGAGUAUUUUGCUUUUCAUGAUCUUGCUCACUGCAACUUCCGCCUCCCAGGUUCAGGCGAUUCUCCUGCCUCAGCCUCCCAAGUAGCUGCGACUACAGGCGUGUAGCACCACACCUGGCUAAUUUUUGUAUUUUUAGUAGAGAUGAGGUUUCACCAUAUUGGCCAGGCUGUUCUCAACUCCUGACCUCGUGAUCCGCCCACCUCAGCCUCCUAAAGUGCUGGGAUUACAGCUGUGAGCCACCCUGCCCGGCCACUUUUGUAUGAUUUCUAAUGUAUUUGUAAUUUACCUAACAAAUUGCCUAAUCUGCUAUGUUAAUGUAUUUAUGAAUUAAAAUAAAUACGACUGCAUGUUUGUGGUUCAUUUUUGUGGAGGUGGCUGUGGUGACAUCAGCCAAGAAUCUGAAUGGUACUGUUGAAGGAAACUAGCAUGAUAGCUUCAGUUCUAAAGGCCCUGAAACCUAGUCUCAGGUGGGUCCCCCUUGGGUUCACUUUAUAUUGGCAGUUUAUUGGGAAAAUGGAUAUUAGGUCCUGACCAAUAGGACCGUAAGUCUGGGUUGAGUGCAAGAUGAGUUAGACCGAUUCUUUAGCUUCCUGCAGUGUAGUGGAGGAAAAAUCGAUGGUAGCAACGGGAGGUUGUAUCCCUAGCUGAUGAGUUGUAUGAGCCUCUACUACCUGGCGCACCUCCGCCUGAAGAUUGCCAGAAUUGCUUGCCUCAUGACGUGAGUCACAAUGGAAACUUUGUCAAGCCCCCUGCACUGGCUGCCAACAUAAAUGUUCAGUACCCUGAAGGAUGGGACUGAAGGGGGAUCAUCUAGAAGGUAAAGUUACCUACUGGCAUAGGGGAGGUGGGACAGCCGUUAAGCCAUUUGGAACUUGAUGGAGACAGGUUUGAGGGAGGUGGGUGAGAUUGGAGUUUGGUGGACUGUAGAGCUUGCUUGCCAAGGUGUUGAGGUCAGGGUUGGUUUGAGAAUGGAAGCUAGUUACUAGCUAUGAUUGUGGGGGAACACAGCUUGAUUUUUCUUACAAGCUAAGAGGAGUGAGGCAGUGUUUAAGAGGGCAUGUUAAAUGCAGCCAGGCUUGGUGGCUCACACCCGUAAUCCCAGCACUUAGGCUAAGGCAGGCGGAUCACAACAUCUAGAGAUCCUGGCCAACGCGGUGAAACCCUGUCUGUACUAAAAAUACAAAAUAACUGGGCAUGGUGGUGUGCACCUGUGGGAGGCUGAGGCAGAAUUGCUGGAACCCGGGAGAUGGAGGUUGUACUGAGCUGAGACCUUGCCACUGCGCUCCAGCCUGGUGACAGAGUUAAGUCUCAAAAAAAAGGCAUCUUCCUAAAGCAAUUGUAUUUGUGCUUACCUGUGCCAGGCACUGUUCUAGGUAAGCACUAAGUGGGCUUUAAUACAGCAUAUUCCAAUGGGGAAUCCCAGGAACCAAAAGACUAAUUGUCCAAGUCCACAACUAGAAGUGGCACCUCUGCAGAAACAAGCAUCAAAUUCCCUGCUCAGGAAGAAGCCAGAUGAGUCAGCCCCAUUCGUCUGUAUGCCCAGUCCCAUCCGUGUCCUGCUGUAACUACAUAGAUCUCACCUGAGUAAAGUGAUUUUUUUCUGAA

Taxonomic tree

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Publications