Caution, this is an AI generated summary based on literature. This may have errors, see here for more.
Please share your feedback with us.
spu-mir-137: spu-mir-137 is a microRNA that is predicted to influence the expression of AjC3, a target gene in the sea cucumber, A. japonicus [PMC4669494]. In a study comparing A12 vs. A00, no miRNA was down-regulated, but spu-miR-133 and spu-mir-137 were found to be overexpressed [PMC4669494]. The expression of AjC3 showed a tendency to decrease at the fourth time point (12 h) [PMC4669494]. The mature and hairpin sequences of spu-mir-137 in A. japonicus were found to be the same as those in S. purpuratusis [PMC4669494]. To determine the evolutionary relationship within the miR-137 family, alignment of full-length sequences of spu-mir-137 hairpins with miR-137 from other species is necessary [PMC4669494]. In comparison to vertebrate members of the miR-137 family, spu-mir-137 showed an offset at the first nucleotide [PMC4669494]. At the second time point (6 h), two down-regulated miRNAs (spu-miR-133 and spu-mir-137) were observed in A06 vs. A12, but AjC3 began to increase in expression level [PMC4669494]. Through bioinformatics analysis, five target genes were predicted for various miRNAs including spu-miR-133 and spu-mir-137: novel 45, spu-miR2004 and 2006 as well as A. japonicus complement C3 or C3–2 genes [PMC4669494].
Genome locations
Gene Ontology annotations
Ancestor Chart
Loading ontology ancestors...
Failed to load QuickGO Ancestor chart
Sequence
Sequence features are shown above as colored rectangles.
Zoom in and click to view details, or
Reset