hsa-mir-4500: Hsa-mir-4500 is a potential core miRNA that plays an important role in the development and prognosis of breast cancer (BC) [PMC8194198]. It is part of a miRNA-mRNA targeted network that includes several other miRNAs, such as hsa-miR-103a-3p, hsa-miR-107, and hsa-miR-133b, which have targeted relationships with hub genes [PMC8194198]. Hsa-mir-4500 has also been found to be differentially expressed between acute myocardial infarction (AMI) patients and normal controls [PMC6388335]. It has been identified as a potential biomarker for dilated cardiomyopathy (DCM), along with other miRNAs such as hsa-miR-5682 and hsa-miR-32-3p [PMC9157606]. Hsa-mir-4500 has also been found to be involved in processes related to preeclampsia and colorectal cancer (CRC) development [PMC9601722] [PMC7582694]. Additionally, it has been identified as one of the miRNAs that could potentially target ACE2 and TMPRSS2 receptors, which are important for SARS-CoV-2 infection [PMC8722767]. Overall, hsa-mir-4500 is a versatile miRNA that plays a role in various diseases and biological processes.