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Homo sapiens (human) hsa-miR-320c URS0000010D30_9606

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hsa-miR-320c: Hsa-mir-320c is a microRNA that has been found to be upregulated in plasma extracellular vesicles (EVs) in patients with progressive disease (PD) compared to those with partial response (PR) [PMC8121992]. The levels of hsa-mir-320c, along with hsa-miR-320d and hsa-miR-320b, were significantly higher in the PD group, indicating an unfavorable response of these microRNAs to immunotherapy [PMC8121992]. In a study using a cut-off at logCPM>4, p<0.05, and FDR≤0.1, hsa-miR-320d was identified as the most significant differentially expressed (DE) microRNA. Hsa-mir-320c was also found to be differentially expressed along with hsa-miR-642a-3p and hsa-miR-320b, with FDR values around 0.1 [PMC7057418]. These findings suggest that hsa-mir-320c may play a role in disease progression and could potentially serve as a biomarker for monitoring response to immunotherapy [PMC8121992][PMC7057418]. Further research is needed to fully understand the functional significance of hsa-mir-320c and its potential implications in PD and immunotherapy response.

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Gene Ontology annotations

Sequence

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AAAAGCUGGGUUGAGAGGGU

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This sequence is found in 4 other species

Publications