HOXB-AS4: HOXB-AS4 is a long non-coding RNA (lncRNA) that is encoded by the HOXB gene cluster. It is one of the 18 lncRNAs identified in the HOX gene clusters, which are located in four regions: HOXA, HOXB, HOXC, and HOXD [PMC9819025]. In various cancers, including cholangiocarcinoma (CCA) and clear cell renal cell carcinoma (ccRCC), HOXB-AS4 has been found to be differentially expressed and associated with prognosis [PMC6180422] [PMC10082204]. In ccRCC, a lncRNA-based signature including HOXB-AS4 has been developed to classify patients into high-risk and low-risk groups based on overall survival (OS) [PMC6886334]. Additionally, in pancreatic cancer cells, specific methylation of HOXB-AS4 has been identified [PMC7056837] [PMC8806254]. Furthermore, co-expression analysis has revealed correlations between HOXB-AS4 and other lncRNAs within the same gene clusters [PMC8602076]. The prognostic effect of higher expression levels of HOXB-AS4 has been observed in various cancers such as ccRCC and lung adenocarcinoma (LUAD), where it is associated with inferior OS [PMC10082204] [PMC8957844] [PMC8602076] [PMC7756030]. Further research on the molecular characteristics of lncRNAs such as AC007907.1, AC025419.1, AC078993.1, AC090241.2, AL158166.1 AL355974.2 AL596330.1 KLHL6-AS1 LHX1-DT LINC00528 LINC01436 TTTY14 will provide valuable insights into cancer development and progression as well as potential therapeutic targets [PMC6886334].