hsa-mir-616: Hsa-mir-616 is a microRNA (miRNA) that has been studied in various contexts [PMC4526194]. In one study, four miRNAs, including hsa-mir-616, showed differences during differentiation, suggesting an interaction between status and differentiation variables [PMC4526194]. Another study suggested that hsa-mir-616 should be further evaluated to determine its role in ovarian cancer survival [PMC8148489]. In a functional assay, the presence of hsa-mir-616 efficiently reduced luciferase expression in a specific plasmid compared to another variant (P < 0.05) [PMC4505847]. This finding was consistent with in silico analysis and suggested a functional interaction between hsa-mir-616 and the target mRNA [PMC4505847]. Further functional assays indicated that hsa-mir-616 may affect mRNA expression by degrading it [PMC4505847]. Additionally, an integrative analysis showed that certain single nucleotide polymorphisms (SNPs) may change the binding activity of miRNAs, including hsa-mir-616, with the target gene [PMC4505847]. Another study found that hsa-mir-616 was one of the miRNAs significantly affected by vitamin D treatment in SCC-25 cells [PMC7551909]. Overall, these studies highlight the potential role of hsa-mir-616 in various biological processes and its potential as a therapeutic target or biomarker.