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Homo sapiens (human) HORMAD2 and MTMR3 antisense RNA 1 (HORMAD2-AS1) URS0000EEACE2_9606

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HORMAD2-AS1: HORMAD2-AS1 is a long non-coding RNA (lncRNA) that has been identified as closely related to the prognosis of lung squamous cell carcinoma (LUSC) based on bioinformatics analysis [PMC10111779]. In high-risk LUSC patients, HORMAD2-AS1 was found to be highly expressed, while the expression of other m6A-related lncRNAs, including AC138035.1, AC243919.2, and AL122125.1, was downregulated [PMC10111779]. A risk model for LUSC prognosis was constructed using two m6A-related lncRNAs: AL122125.1 and HORMAD2-AS1 [PMC8637334]. In the TCGA-LUSC cohort, six lncRNAs (AL122125.1, AC138035.1, AP001469.3, AC243919.2, HORMAD2-AS1, and PRC1-AS1) were significantly correlated with the survival of LUSC patients [PMC8637334]. The expression of AL122125.1 and HORMAD2-AS1 showed significant differences between LUSC tumor tissues and normal tissues [PMC8637334]. However, there were no studies reporting the prognostic values and biological functions of AL122125.1 and HORMAD2-AS in tumors [PMC8637334]. Further analysis showed that AL122125. 13 m6A-related lncRNAs were identified as prognostic lncRNAs in LUSC patients by univariate Cox regression analysis including HORMAD2-ASl [PMC9641337].

Genome locations

Gene Ontology annotations

Sequence

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AGCAGCCGCCUCUCAGCCACGGGCUGCACACUGACCCGACGCGACCUUCGGUCAGGGGCCGCCAGCCUGGGCCACCUAUACAACGACAGCCUGCUCCGGGGCUUCCUGAGGAGGUGCCUGCCCCGCCGAGGUUCAACAGCUUUGGAGAGCAGGACAUCUUUUCCUCUCAGCCUGGCCCUCUGCAAUGGAGGCCAUAAAUAGGCCAGUAGUGGAAGCUACAGAACACGUGAGCAUGGCAGGGGCUGAGCUCCAUUUCAAGAUAUGGGUAAGAGGAGGGAUGCUGUUGCCUUGGAGCUGCCAGGCUGCAUGGCAGACAAGCAGGAUUCCUGCUGCCUCCCAUGGAGACUAUACUGGAACGCAGGUCUUGCCCUGUCAUCCAGGCUGGAGUGCAAUGGAUCUUGGAUCACUGCAACCUCCACCUUCCAGGCUCAAGUGAUCCUCCUGCCUCAACCUCCCAAGUAGCUGGGACUACAGUUCAAGGAAAGAAGCAAACUUAUUAUUUAAGAGCAAUGCAAAAUGAAAGCCAAGGCCAAGGACUUACUUUCCCGGAUCUGGCAUCUGAGUGCACAGCAACCGCAGAGACUGAAAACUCCUCCGAAUAGAAUGAAUGUUUGCCAUCCCCAUAAACACAACUUCACAGUUUGGGUAAUACUCUGGAGAGAGUAACAAUAAAGAGAACACAAAUACGUUGAACUUAAAGCCCACAUGGCCAAAUUUAAAAGCAAACUGGCUAUAAAACAAACCCACUGCAGCUUCUGAUUAACGAAACUGAAAUGUUUUGAAAUGCUUAACUAUUAGCCCAAUCCUUUAUAAUAAGAGGAACACACUGAAUUUUAGCUAUCUUUUCAAAAAGCGUGAAAAGGGAAGGUUAGAUUUGUAAAGAAGAUACUGACAUAAAAUAAAAGCUAUUAUUUUUUAAAAGAAA

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Publications