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Homo sapiens (human) WDFY3 antisense RNA 2 (WDFY3-AS2) URS0000CCE129_9606

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WDFY3-AS2: WDFY3-AS2 is an antisense long non-coding RNA (lncRNA) that functions as a regulator of its complementary protein-coding gene, WDFY3 [PMC6064140]. In glioma, the expression correlation between WDFY3-AS2 and WDFY3 was investigated to understand the potential function and mechanism of WDFY3-AS2 [PMC6064140]. It was found that WDFY3-AS2 directly binds to miR-18a in EC [PMC8203383]. Furthermore, the expression of WDFY3-AS2 was observed to be lowest in the basal subtype [PMC7219740]. To assess its role in cisplatin-resistant ovarian cancer (OC) cell migration and invasion, Transwell assays were conducted [PMC8164817]. WDFY3-AS2 is an antisense lncRNA that has been shown to regulate its complementary protein-coding gene, WDFY3 [PMC6064140]. It has been found to directly bind to miR-18a in EC [PMC8203383], suggesting a potential role in post-transcriptional regulation. In glioma, the expression correlation between WDFY3-AS2 and its complementary gene was investigated to understand its function and mechanism [PMC6064140]. The expression of WDFY3-AS2 was observed to be lowest in the basal subtype, indicating a potential subtype-specific role for this lncRNA in glioma development or progression [PMC7219740]. In cisplatin-resistant OC cell migration and invasion assays, the function of WDFY3-AS2 was further assessed. Transwell assays were conducted to evaluate its impact on these cellular processes. This suggests that this lncRNA may play a role in promoting or inhibiting OC cell migration and invasion under cisplatin-resistant conditions [PMC8164817].

Genome locations

Gene Ontology annotations

Sequence

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CUACUGAGCCGGCCGCAGAAAUUGCAGCCGCUCAGCUUCUACCCCCUCCUGCCUUUCCUUCCUCUUUCCUUACUUCCUUCCCUUCCCUCGGCUUCCCGCUCUUGCCUCACUCUCAGCGGCUGCCUUCGCCCCUGUCUGCAGACAGCGCCGCUGGAUGCUCCCAGCUGGACUUCAACCCCACUCCUCUCAGUCCCUCUCCCCACUGCCUUCCAGACGCGCCUCUUCCCCGCCCCGCGCCCCUCUCUCCUCUCCCACCCCUGCCCCUCUCCGCGGCGCUCACCCUCCUCAGUCCCAGUUUCUGAAAGGACUCAGCUGAGAAAGGACAACUGGGUUCCGCUUUCCUUAACCCUACACCCUUUAGCUGGAUGCUGUCAGAGGCGAUGGAGAAACGCAAAGGCUACUAGACGCAACAAUAGAAUUACCAUAUUGUUUUUCCUGGUUUGAAAGGACCAGAUGGAAAGAAACUGGGCAAGCCAAUGAAAGUCUCUGGGGAUCAUGGGAAUUGAGUGUCUAUGAAAACCAUAUUCCAGACAAGAAUAUAGUCUAAGGACACAGCAAGAGGCAACAUUUUGGAAGCAGAGGGCAACUCUCACUGGAAACCAAAUCUCCUGGCACCUUGAUCUUGGAUUUUACAGCCUCCAGAACUGAUAGCUGGGAGGCAUUACAUAGUCAUGUGCGAGGUCAAAACUGAGUCACCACCACAACCAAGUUCCAGCUGGCAAGAAGAGGAAAAAUAACACAGAGGAGUUAUGACCAGUGUUGUAAGGAUCUGGCCUAGAAAUGGCAUGCAUCUCUUCCACUAAUAUCCUAUUGGUAAAAAUGUAGUCACAUGGGCACACCACCUAUCUGCAUGGAAGGCUGGGAAAUGUUGAUCGGUAGGGCAGCCAUAUGUGUAGGAAGGAGAAAACAGAAUUUGGUGGAUACCUAGUAGUCUCUGCCAUACCCUUGACCAGAAAUUUUUCUUCUAAAGAAUUUAAUUCUAAAAGUUAUAGACAUUCCCAAAGAUAUACCUGCAAGCAUCACAGCUUUGUGUAUAAUUGCAAAAGUUGAAAUCAACAUGAAUGCCCAAAAUAGUGAAUUAUUUAAACAGAUUAUUACCCAUAUUAUGAAGAAAUACUCUGCAACUCUUAAAAAUAAAUGUAAUGUGCCAGGCGCAAUGGGAUAUGCCUGCAGGCCCAGCUACACGGGAGGCCAAGGCAGGAGGAUCACUUGAAAUCAAGAGUUCAAGUCUAGCCUAGACAACAUAGUGAGACUUGGUCUCUAAAAAAGAAAAAAAAAAAUAAAACUGAUGUAAUGAAUAUAUAAUUACAACAAAAGAGGUCUAACACUAUAGUAGAAAAGUUUGGGGCACUCAUCCCAUUCAUAAUUAUUUUACAUUUAAAUUACUGUUCCUACUUAAGUGGUGAGCUUGGUAACCAUUUUCAUAUCAGGUGAUACUGCUGCAGUAAUCAUAGCUGUUUGAAUCAGGAAUAAUCCCAAUCACAUUUUCUCUUAAUCGUUUAUUAUACUGGGCAUUGGGGUUGCAAGAUAAUGCACAGUCCGAGCUCAAUACAUGUCUUCAUGUACCUGUAUGUAAAUCCCACUUUUAUUCUAAAAUUCUUUGAAUAUUUUGUUUCUUGGAACCCAAUGAUCCUAAGAAAAUUAUGUACUUUUACCUGAAAAUUAAAACCAAUAUUUAUAAAAAGUGUAUAUGCAGUAUGAUACCACUUUUAAAAAAAGAUAAAUUUAUAGAAAAAAGUUUAUAUGACUGACAACAAUGUCUCUGAGUGGUAGGAUUACAGUUAAUUUUUAUUUUCUUCAUUCUACUUAUCUUUAUUUUCUGAACUUUCUACAAUGAACAUGUUUUAUUUUUACUUUUGUUAAAAUAAAUAACAUUUAAUUUGACGGAAAAUUCUAAAAAUCAACAUUUGGUAACUUAAAUAUUCAUUGGCACAUGAUUCUGUGCCUGUUUCUGGGGGUCAUUCCCAUGAGAAGAGCAGGUAGAACUUAUGAGAAUAGAGCAGUCGAAAUAUUAUAGGUUUCAUAUUUUACGGCUUUAUUGAAAACAUUGAUAUAUUGAAUAUUCAUAAAUUUUAAUUUAACUUUCUUUUAUAAUCCUUAAUGUGAGGCUAAGGUAUAAGGAGAAAGGAGAUUGGUAAGGAAGUGUGAUACAUAUUGAAUCAGGUGUCAAGGUACCAUUUGUGCCUGGAUCUGACCAAUAGACCAAGGUAAAAAUCUCAAAGAAUGAGACUUGUAAUGAGAAUGCCACAAACUUGAAUACCUUAUGCACAAAACACAAACAUUGUUAUGCAUAAUGUACAUGAACCCUGAAACAAAGAUAAUGAUUUGGACCACCCAACUGAAGUGGCAUGUUAUGUUUUUGGCAUGAACAAAAGAAACAAGAGAGAAAAAAAUCAAAAUAAUUAAAAUAAAUUGUUAGAGAAAAGUUACUUUAAAAAUAGCUAUAACGCUUUGCAAUUUCAGUAACAGUUCUGCCUCUGAUGCAAUGUAAAACAUGUAUUAGACAUUCAGGCUCCACAAUAAAUUUUAAUGAGCACUACAAAUUUAGAAUAUAUAAAAAUAUCAGUAACCUAUGAAUUCAUCAACAUAACUCACUUUUCAGUUAAGUUAGGCUGAGUUGAAAUUCUACUAAGUUUUCCCAUAUUCUUGAUAAAGGCUAAAUUUGAAAUAAUUUAUUUAGAUGACUAAUUGGCAAUUUGAUAGUAGUUACAUUUUAUGUAACACUUGAUAUAAUAACCCAAAUUAAUUAGCUCAAUAUUAUCUUCUGUGGUUUAUUGAUCCAAAAGUACAUAUUUGUUAUGUAAACUUAUACUAUGUAAACUUGAAUUAGUUUUUUGCUUCCUUGAAUUAAUAAAGCCCAUUAAUGCAAAUCUAAGCCUUCAUAGACUUUUCCAAUCCUUAGUUAAAUAUUAAAAACUGAGUAUUGUAGUUAUUUGCUAGGUAUAAAAGGUGACUCAGAGUAGAGAGUAAGAUGUCAGCAAAUAGACAAUAAGAUGUCAGCAAAAGUGCCUCAAAUUUUAACUGCGUCAAGUUAAGGGCAUUGUAAAUACUGUAGUUUUAUGUAGCUUGCAACUUCUACUGAAAUGAGUUUAAUCAUGUCUUUCACAUAGCUGAAGUUUGUGUCAAGAUUUAAGCUGAUUUUCUCAUUCUUAUCAAAGUCUCACCUGGGGGUAGGGAGGGGUAGGCCUACCUCCCACCUCUAUACUAUCAUUUUAGGAACAGACAGGCAUAAAUCUGUUCAUAUGGUAGAACACAUGAUGUUAGAGUAUAUUUUGUUGAAUGCUAUGGAAUAUUAAUAUAAUUAAUUCUAAAAUAUCACCUAAAAUAUGUCAACUGAAGAUCUGACUGUACUAAAUAUGAAAAAUAAAGCAGCACAUACUUUC

Taxonomic tree

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