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Homo sapiens (human) family with sequence similarity 157 member A (FAM157A) URS0000ABD871_9606

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FAM157A: FAM157A is a long non-coding RNA (lncRNA) gene that has been found to have dysregulated m6A modification levels after silencing of METTL14 in HepG2 cells [PMC9647857]. It is one of the genes that show statistically significant differences in plasma between healthy individuals and those infected with influenza [PMC4835085]. FAM157A is recurrently affected by HBV integrations and has been found to be more frequently integrated in tumor samples compared to non-tumor samples [PMC8398950]. It is a member of the Long non-coding RNAs with the FAM root symbol [PMC8398950]. FAM157A is overexpressed in blood and has been associated with poor prognosis in invasive breast carcinoma [PMC7874462] [PMC7285808]. It has also been linked to cancer-related pathways, including 'p53 Signaling' and 'Molecular Mechanisms of Cancer' [PMC9813548]. The expression of FAM157A is significantly associated with the expression of ITGAM and FPR1 genes [PMC8266366]. In summary, FAM157A is a long non-coding RNA gene that shows dysregulated m6A modification levels, significant differences in plasma between healthy individuals and those infected with influenza, recurrent HBV integrations, overexpression in blood, poor prognosis in invasive breast carcinoma, association with cancer-related pathways, and significant correlation with the expression of ITGAM and FPR1 genes.

Genome locations

Gene Ontology annotations

Sequence

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GCAAGUCAAGGAAGUUGCUGCCCAGAAACCAAGUGAGGACAUUUACAAGAACUGGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACUGGAUUUGCUUUUUCACCAGAGGAUCCAGAUUUCCCUGUGGCCUCGCAAACAAAAAAGAAGGAAGACGGAGCAGCACAGUCAUCCCUUUGUGAAAAAGGCAUUCAGGUUCUCCGCCGGCUCUGGCUGCGGGCGGCCCUCAUCUAACAAGAUGCUUCGGUCCAUGGGUGGAGGACAAAGGCCUACGGGCUUGGGGAGCGAGUUCUUUCGUCUCCUACAUGACCUUCAUCUGCUCGCGUUUGCCAUGAAGCGCAUCUGGAUCCACCGGAGGGGCGAGGCCACAGCUCGACCGCGAGCACCUGAGCAUCCUGCACCGCCUGCGACGGCCGUCAGGGGGCGCGAUGCCGCCUCACAGAACCUCAAGCGGCGCCCGGGUUCCGGCACAGACGGCCUGCGGCUCCAGGGGGCGGAGCCGAGCCGUCUCCUCAGGACCUACGCAGGAGGCGCCGUCAUCCCUACAGGGACACCUGAGAGGGCCCAGCCUCCUCCUCCUCAGGACCCACUCGGGAGACGCCGCUGGCUCUCUAGGAACACCUGGGGACCGUGGCCAGGGACGACCCAGCCUCCUUCUCCUCAGCUCCUCAGGAACGACUGGGGAAGCUGUGGCUUCAUGGUCCCCGAGGCUGCCCGAGGAAAGGUAUUUCAGGACAGCCAGGAGGGGGCGCACAUCCGCCGAGAAACUGUGAGCAAGAGCGUCUGUGCUGAACCAUGGCGCCACCAGAGGGCGCGCGAUCCCGCCCCAACCAACUUCCCGCUGAGGUGCCAGAAGCAGCGAGGAGCUUCAGCUUCCUCAGGGCAGCACGAGGGUCGUGUUAACUUGGUGUUCUUCAUUGAUGAUGAUUAUUCCCCACCUUCUAAGAGACAAAGACCAACGAGCCACCACAGCCACCAGUCCCAGAACCCGCCAAUGCUGGGGAACGGAAAAUGAGGGAGUUCAACUCUGGCCCUCACAAUCCAGUGGAGGAGACGAAACUCAUCUGCCUCUGUCCCUCUGGGCACGCCUCAUGCCAGGUGCAUCUGUGGACAGGGGCCAUGCUCCUGGGCUUCCAAAGUUGGAGAAAGCUGCCAGGCUCAGGUCUGAAGGCCAGAAUUCUACAGUAAGUCCUACUGAGUCAAGGUGGGAGCAGGGUCGGUAGCUUCCGAGGCUCUGCGGGAGAAUCCGUUUCCUGGCCGUAGAGGUGGCCUGCACUCCUCAGCUUGUGCUGCCCGUCUCGAAUGACUGGAGUUUCCUGCUUCUGUCACUACACCUCCCACCCUCUCCAUCACCUGCUCUGCUCUUACAAGGAUCCGAAGAAAUGGAAUCAUCGUAUCGCUGAUCUACGUAAACAAACUGAAGAAUUGUCUGAAAGAAAAUAUGACAUGAACUUAUGAAUUCAACAGGUGAAGAUUUACAACUUGAUAAAUCAACUUUGUCAGCUCGAGCUGUAAAAGCCAAAGGUCCGGUGAUGAUCCCAUACCCUUUUUUCCAGUCUCAUGUUGAAGAUUUUUAUGUAGAAGGCCUUCCCAAAGGAAUUUUUUUUUUUUUUUUUUUUUUUGAGAUGGAGUUUUCACUCUUAUCGCCCAGGCUGGGGUGCAAUGGCGCAACCUUGCUGGUCACUGCAACCUCUGCCUCCUGGGUUCAAGAAAUUCUCCUGCCUUAGCCUCCCAAGUCACUGGGAUUACAGGUGCCCACCACCACACCAGGCUAAUUUUUGUAUUUUUAGUGGAGAUGCGGUUUCACCAUGUUGGCUGGGCCAGUCUCGAACUCCUGACGUCAAGUGAUCUUCCCGCCUCGACUCCUGAUAUCAAGUGAUCUUCCCGCCUCGGCCUCCCAGAGUGCUGAGAUUACAGACGUGAACCCAUGCCUGGCCAGGAAUUUUGUUUUUUAGGAAGGCUUUCUACUAAUGGAAUUCCUGGCCUUGAGAGGAUGUUACUUUAGAAGGAAAGGAUUUUUUUGUUAUUAAAAGCUGGACCUACCAUGAAAGACUUCUGAAUCCAGGAAGAGAAACUGACUGGGCAACAUGUUAUUCAGAAACAGGACCUUGCCCUGUCACUCAGGAUGGAGUUCAGUGGUCCUAUCAUGGCUCAUUAUAGCCUCAAACUCCCAGGCUCAAGCAAUCCUACCAUGUCAGCCUUCCCAGUAGCUGGGACUACAGGCUGGAGUACAGUGGCACAACCUCUGCUCACUGCAGCCUCCACCUGCCAGGCUCAAGCAAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGGGAUUACAGGAUGUGAGCUCACAAUGACUCAAGCUGCCACAUACUGUUGAUUGUGAAAUGCCAGUUGAAGCAUAUGUCCUGCGAGCUUAGGGGUGCUACAAGUUGACCACUGCAGCAGUAAAGAUGACUCUGAAGAAUGGCGUGGGUUGGUUCCUUUCAAAUGCACUUGAGCAGCGGUCUCCAACCACAGGGCCACAGAGCUGGAGCUGGAUCUACCAUGAAAGACUUGUGAAUCCAGGAAGAGAGACUGACUGGGCAACAUGUUAUUCAGGGUCUCCCUCUGUUGUCCAAGGCUGGAGUGUAGUAGUGCUAUCGCAGCUGACUGCAGCCUCAACCUUCCAGGCUGAAGCGAUCCUCCCACCUCAACCUCCCACGUGGCUGAGACUACAGGUGCUUGCCACUAUGCCCAACUAACAUUUGGAAUUUUCGUAUACGUGGAUUCUAGAGGGGUGACAGCGAAACGUGGGACCAUCCAGUUGCAGGAAAACAAGCUUGACACGCCCACUAAUUCUACAUUAUGCUCCUACCUCCCGGCAGCCUCUCCAGGCCCAGAACUUUCUCCAGUCAGCCUCUACAGACCAAGCUCAUGACUCACAAUGGCCUAUUUAGGCCCAUACCCUACGUCACGGCAGCCUCCGCAGAUGAGGCUACUGCCUCACAACAGCCUCCACAGGCACAGCUCCAUCGUUACAAUGGCCUCUUUAGACCCAGCUCCUGCCUCCCAGCCUUCUCUCCAGGCCCUGAACUUUCUCAAGUCGACCUCACCAGGCCCAGCUCAUGCUUCUUUGCAGCCUCUCCAGGCCCAGCUCCUGCAUCUUGGUGGCCCCUCCAGGCCCAGCCUCUGCCUCCCGUCAGCCUCUACAGUCCCAACGUCUGCCUCACAGCAGAUUCUUCACGCCCAGCAUCUACCUCACUGUGGACCCCCCAAGCCAAGCUCCCAACCUUUCAGCAGCUUCUACACACCCAGCUCCCGCCUGCCAGUGGCCUCUUCAGGCCCAUGGGGCUCAUUCCUGACAACGGCCUUUCCAGGCCCAGUUUUUCCCUUCCGGCGGCCUCUCCGGGCCCAGAACCUCCUCAAGUCAGCCUCUCCAGACCCACUUGCACCCUCCGGGCGUUCUCUCCGGGCCCAGCUCUUCUUCCUGGUUGGGUCUCCAGGCCCGAUUCCUGCCUCUCAACAACCUCUUUGGACUCAGUGCCUACCCAUCUCCUGGCGGCCUUGGUCGGCCCACAGCUUCCUCAAGCCAAGCUCCCCAGGCCCAGGUCAGGCCUCACGGUGGCCUCUCCAGGAUGAGCUCCUGCCCUCCGAUGGCAUCUCCAGGCCCCAAAUGGUCUCCGGUCGGUGGGCUCCUCCACGCCAAGGUUGGGCCUCCCGGCGACUGCCGCAGGCCCAAGUUGUCCUGAAGUCGGGCUCUCCCGGCCCUGCCUCCCAGCAAGUAAGCAAGCUCUUUUGGCUCAACUCCUGCCCAGCUCCCAACCGCCUUUGUAGGCCCCGAACUUUCUCCAGCCAAGCUCUGAGGGCCCACCUCCUGCCUCCUGGUGGCCUGUACAGUUCUAGCACUGGUUGGAGAACAGCCUCUGCAGGCCCCGCCUUGCCUCCCAGGGGCCUCUCCAGGCCAAGCUCUUGCACCCACGGCGGCCUCCCGGGGCAAGUCCCUGCCUGCCUCCCAGCAGCCCGCGUGCGCCCAGCUCCUCCCUCACGGUGGCCUGUUGAUGCCAACUCAUGCCUCUGGACCCUGCACAGAGCGUGACGCUGCCUCACACUGGCUACUCCACGCUGAGAGAGGUCAGUGUGAGCCCUUGCCUCACACCGGCUCCUCCCACGCUUGAGAGAGGUCAGCGUGAGCCCCUUGCCUCACACCGGCCCCUCCCACGCUGAGAGAGGUCAGUGUGAGCCCUUGCCUCACACCGGCCCCUCCCACGCGGACAGAGGUCAGCGUGAGCCCCUUGCCUCACACCGGCCCCUCCCACGCUGAGAGAGGUCAGUGUGAGCCCUUGCCUCACCCCGGCCCCUCCCACGUGGACAGAGGUCAGCGUGAGCCCCUUGUCUCACACCGGCCCCUCCCACGCUGAGAGAGGUCAGUGUGAGCCCUUGCCUCACACCGGCCCCUCCCACGCGGACAGAGGUCAGCGUGAGCCCCUUGCCUCACACCGGCCCCUCCCACGCGGACAGAGGUCAGCCCGAGCCCCUUGUCUCACACCGGCCCCUCCCAUGCUGAGAGAGGUCAGCGUGCCCCUUGUCUCACACCGGCCCCUCCCACGCUGAGAGAGGUCAGCCCAAGCCCCUUGCCUCACACCGGCCCCUCCCACGCGGACAGAGGUCAGCCCGAGCUCCUUGCCUCACACCGGCCCCUCCCACGCUGAGAGAGGUCAGUGUGAGCCCUUGCCUCACACCGGCCCCUCCCACGCGGACAGAGGUCAGCGUGAGCCCCUUGCCUCACACCGGCCCCUCCCACGCUGAGAGAGGUCAGUGUGAGCCCUUGCCUCACACCGGCCCCUCCCACGCGGACAGAGGUCAGCGUGAGCCCCUUGCCUCACACCGGCCCCUCCCACGCUGAGAGAGGUCAGCCCGAGCCCCUUGCCUCACACCGGCCCCUCCCACGCUGAGAGAGGUCAGCGUGAGCCCCUUGUCUCACACCGGCCCCUCCCACGCUGAGAGAGGUCAGCCCGAGCCCCUUGCCUCACACCGGCCCCUCCCACGCUGAGAGAGGUGUGAGCCCCUUGUCUCACACCGGCCCCUCCCACGCGGACAGAGGUCAGCGUGAGCCCCUUGCCUCACACCGGCCCCUCCCACGCUGAGAGAGGUCAGUGUGAGCCCUUGCCUCACACCGGCCCCUCCCACGCGGACAGAGGUCAGCGUGAGCCCCUUGCCUCACACCGGCCCCUCCCACGCUGAGAGAGGUCGGUGUGAGCCCUUGCCUCACACCGGCCCCUCCCACGCGGACAGAGGUCAGCGUGAGCCCCUUGCCUCACCCCGGCCCCUCCCACGCUGAGAGAGGUCAGUGUGAGCCCUUGCCUCACACCGGCCCCUCCCACGCGGACAGAGGUCAGCGUGAGCCCCUUGCCUCACCCCGGCCCCUCCCACGCUGAGAGAGGUCAGUGUGAGCCCUUGCCUCACACCGGCCCCUCCCACGCGGACAGAGGUCAGCGUGAGCCCCUUGCCUCACACCGGCCCCUCCCACGCUGAGAGAGGUCAGUGUGAGCCCUUGCCUCACACCGGCCCCUCCCACGCGGACAGAGGUCAGCGUGACCCCCUGCCUCAACAGGCCACCGUGAGGGAGGAACAGGAUCGCACUCGGGCUGCUGGGAGGUAGGCAGGGACUUGGGCCUGGGAGGUCGCGGUGGGGCGAGAGCUGGGCCUGGAGACUCCCCUGGGAGGCAACAGCGGGGUCUGCAGACGCCCUUCUCCAGCCGGAGCUGGGACUGUUCAGUCACUGGGAGAAGGGAUGUGGGUCUGAAGAGCUUGGUUGCAGAAACUUCGGGGUCUACAAACGCAGGCGGGAGCUGAGCCAAAAGAGCUUGUUUGCUGGGAGGUGGGAGAUGCAGCCAGGAGGAACAGCUGGGCAAUGCGGGAGGCAGAGCCAGGCCUCCUCAAGUUGGCCUCUCAGACCCACUUGCAGCCUCCCGGCGCCCCCUCCGGGCCCAGCUCUUCCUCCCGGCUGCAUCUCCAGGCCGGACUCUGGCCCGACUCCAGGUCCCAACAACGUCUUUGGACUCAGCUCCUGCCCAGCUCCCAGCGGCCCUGGUAGGCCCACAACUUCCCUAAGCCAAGCUCCCCAGGCCCAGCUCAGGCCUCGCGGUGGCCUCUCCAGGCUCAGCUCCUGGCCCUCCGAUGACAUCUGCAGGCCCCAAAUGGCCUCCGGUCGGUGGGCUCCUCUAGGCCCAGCUUGGGCCUCCCGGCGGCCUCCGCAGGCCCAAAUCGUCCCGAAGUCAGUCUCUCCAGGCUUAGCUCCAGCCUCCCGGCGGCCUCUGCAGGCCCAAGUCGUCCUCAAGUCGGCCUGGAAGUGGGCCUGGAAGAGCAGCAAGUCGGCCUCCCUGGGCCCAGCUCCGUCCUCUCGACGGCCUCUCCAGGUGCAAAACUUCCUCGAGUCAGCCUCUCCAGGCCCAGCUCCUCCUGCCUCCCAGUGGCCUCUUUCAGCCCAGCCCAGCUCAUGGCUCUCGGCGGCCUUCGCAGGCCCUGCUUUUGACUUUUGGCAGCCUCUUCAGGCGCAGAACUUGAUCUCCAGUCGGCCUUUGCAGGCCCGGCCUCCUGCCUCUCGAAGGCCUGCACGGGCCCGGCCUCGGCCUCGGCCUCACAGCGGACUCUCCACGCCCAGCUAGCUCUCGCCUCACUGCGGCCUCCCCAGUCCAAAGCUCCUGCCUUUCGGCCACUUCGGCAGGUCCAGCUCCUGCCUGCCAGUGGCCUCUUUAGGCCCAGCUCAUUCCUCACGUCGGCCAUUCCAGGCCCCGUUUUUCCCUUCCGGCAGCCUCUUGGCCUCUAAUUUGUUUAUCUUUUGUGUAUAAAUCCCAAAAUAUUGAAUUUUGGAAUAUUUCCACCAUUAUGUAAAUGUUUUGGUAGGUAA

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