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Homo sapiens (human) IGF2 antisense RNA (IGF2-AS) URS0000A76E5D_9606

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IGF2-AS: IGF2-AS is a long non-coding RNA (lncRNA) that has not been extensively studied in the context of sepsis [PMC8786475]. A study using the RIP assay demonstrated that IGF2-AS expression was higher in cells treated with AGO2 compared to cells treated with IgG, suggesting its potential interaction with AGO2 and involvement in post-transcriptional regulation [PMC9175095]. Silencing of IGF2-AS has been shown to downregulate CREB1 expression by sponging miR-195, potentially inhibiting the development of gastric cancer [PMC9175095]. Furthermore, high expression of IGF2-AS has been associated with longer overall survival in patients with non-small cell lung cancer (NSCLC), indicating its potential prognostic value in NSCLC [PMC7535691]. While the role of IGF2-AS in sepsis remains largely unexplored, it appears to be involved in post-transcriptional regulation and may have implications in cancer development and prognosis [PMC8786475] [PMC9175095] [PMC9175095] [PMC7535691]. Further research is needed to fully understand the functions and mechanisms of action of IGF2-AS [PMC8786475].

Genome locations

Gene Ontology annotations

Sequence

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UCCUAGGCCCGCGGGCUAGAGGCACUUUACCGCCCGGCGGGAGCGCCUCUCCUCCGCGUCCCUCGCCCCAGCCCCCUGCCCGCCCCACUUUGGGACCCUCCAGCCGCUUUCCCCACAAAUGAGAUCUUUGCAAUGAGCAAACGAAAGUGGCGCGGAUUUCGGGGCGCCCAGCAGGAGCGAGCGCAGCCGCCAGCCGCAAGUCCGCAGCCGUGUCCCGCGCCCCACGCCGGCCUCCCCGGCGGCAGCCGGAGACGAGCGCCAGCACCGGCGGGACAGCAGCAGAUGCGGGCCGAGAGCCGGUCAGGGGCGCAGAGGCGGAGGGGAUCGGCGCGGCGGGGAGCUCACCGCGAAGCUGGAGGCUGCGUCCGCGGGCGCACCAGGAGCUCAGGCAGCGAGCGAUCGAACGCUCUGUGGCAGGCGGUGGACGCUGCUGAAGCUCUGGCUCUGAGCUCACCGCUCCGCCGUCCGUGGGACCAAGCCCAGCAUUUUACAAACCCAGCUCCUUUCUCCAAGGGUCCUCAGAGCGCCCCUCCGUCACCCCCUGCAGGGCGCCGCAGACGAGGCGCUGACCUUGCGCUCACUCCCCUCGCUGGGGAAGGACACACUCGCUGGCGUCAGCCCGGCCGGCCUGGGAAGUAGGACUAAGGACCCGAACUGCAACCCUCCACACCAGACAGCACAGACCACCCCAAGGCUGCUCAAUCUGCCCAAAGCCAAAAGAGCUCCCCUGCCAGGACCUCGGUGCCGUGGAGACUGCGGGGAACCUGCUCUGCCCACACCUGCUCUGGCCCCUAGACGGAAGCACCUGGAGCCAACCACGGAACUCCAGAUCCCAGCUGUGUGACUGAAUCCACGCCAGCCUCUCUGAGCCAAAGCUGCUUGCAGAAGGGGGAGAUCCCAGUUCGAAGACUCCCGCGCAGAGCCUGUGGCCCUCUCUGCCAGGCCUCAGGGUGCCUGAGACACUCACCUCUCUGCCUCGCAGUUGGGGCUGAGGCUGGGGCUGGCUGCCAGCCUCAGUUCUGGGAGCGCUGGGGUCGCCUGGGCCACAGGCCACAGCAGCUCACCUCAGGACUGGGCUCUCUGGCCUGCUGGGGCUCAGGCUGUGGGGCAGGCUGGGCAGGGGGCUGAGCUGGCAGCGAUUCAGAGCCCUGGGGCUGGGGGCUGGAAUCCACCUCCUCCCACACAAGCUCGGUGGUGACUCUUCGGCCCCUGGGGAAAAACAAAAAGAUAUUGCUGAGAUGACCUCUUUUAAAAGCAAAGCCCCCCUCCCCAUACACCCCAAGCCUGAGCCCUGUCCCAUCCCCCUCCCCGGGUUCCUUCAGGUCACCUUGUCAGGAUCUGGGCAGCGGCUUCCCCCUCUAGCCCCUCCCCUGCCUAGAGCUCCCUCUUUCAAAGUAUAAGGGAGGGAAGAAGUGGUGAGAAGUUUGCCUAGAAAGGGCUUCCCGGUGCUGAUGGAGAGGCCGAGACCCUUCUGUUGGACAGGCUGCCCUGUUCCUGGGUGAGGAUGGGCUUCUGCCUGGCACUGGGGGUGGAGGGUGCACACGAAUGGCCCGCCUUGAGGGGUCAUGGCACGGAAUAUGAAAGCCUCCUCCACCUCCAAACACCCCCACCUUGGAAGGAGAUAAGGAGGGGGCCCCAGCAAAAGCCACUGGACACACAGCUCUGCUUGACGAGGCCAGUGAGGGACGGCGUGGCUGUGCUUCCUGGGGAAAUGAACCCCCUCCCCACAGACACCACCCUGGGUGGAUCGAGGAGUCUGGGUCCAGGGUGCAACAGAGAAAAACUUCAUGCAUGAAUGAGCAUUCCCAGGGAAACUGCCUUGGCCCCAGGGCGCCUCUCUGUGCCAGGGAGGCUGGGAGAGCAGCAAGGGGGACCAGGUGCGCCAUCAGGAGGAGAGAAGCUAAACCUAGGGGGGACAUGGAGGGCGGUUGUUGCCUCUCCCGGCAUUUCUCCUCAGUCUCCUGUCCAAUUUCUUGCUGGUGGUCAGGAGGCAUAGGGAGGCAGGAGGGAAGGAAGCUUUACCUGUAAAAUGGUGUAUAUAUGUAUAAAUAAAAUCUCUGCGCCAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

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Publications