v24

Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Homo sapiens (human) POU6F2 antisense RNA 2 (POU6F2-AS2) URS0000A76D4A_9606

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

POU6F2-AS2: POU6F2-AS2 is a long non-coding RNA (lncRNA) that has been studied in various cancer types. Using miRcode, 10 miRNAs were predicted to have high binding potential to POU6F2-AS2, and two of these miRNAs, miR-125b-5p and miR-223-3p, were found to be expressed at low levels in lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) [PMC10120888]. These two miRNAs were selected for further experimental validation. POU6F2-AS2 has been implicated in the regulation of cell survival after ionizing radiation (IR) in esophageal squamous cell carcinoma (ESCC) cell lines [PMC6142629]. Additionally, POU6F2-AS2 and another lncRNA called DNM3OS have been found to be involved in DNA double-strand break repair in ESCC [PMC7352793]. However, the specific functions of POU6F2-AS2 in non-small cell lung cancer (NSCLC) have not been explored yet [PMC10120888]. Overall, these findings suggest that POU6F2-AS2 may play a role in the development and progression of various cancer types through its interactions with specific miRNAs and involvement in DNA repair processes.

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences 
AAAAGUACCUAUCUAGGGAGGAGCCAAGAUGGCCGCAUAGGAACAGCUCCAGUCCACAGCUCCCAGCGUGAGCGACGCAGAAGACGGGUGAUUUCUGCAUUUCCAUCUGAGGUACCGGGUUCUUCUCACUAGGGAGUUCCAGACAGUGGGCGCAGCAGGCUUUUCUUCUUGGAGCUGAAACAGGCGCACUGGCGAGGGUUGUGAGGAAAGGUUUGCAGCCCCCUGCCUUGGUCUGCUAUAGCCAGUGACACGAUCAAUACCAGGGUGAGCAGCAGAGGAAGCUCAGGGAAGAUUAUGAAGAUGAGAAUUCAUUACCUAUCAAAGAAAAUGCGUAAACUCUAGAAGUAUUGCUUGCUCCUUUGCCACAAAGUGUACAUUCAAGAGUAAAUUGUUUAAAGCCAAAGGGCCUUGCGCCACGUCCUUAGCCUCAGCUUUCUACUUGCUAAAAUGGAAAUAACAACAGUACCUACCUUACAGACCUGGCGUGAGGAUUAAAUUAUACCAGCAAAGUGCCUGGCACCUAGAAUUUGCCUGAGUUCUGAUCAAUGCUAAAAACACCAUUUAACAGUGCCCUUUCCUGCCUGGGAAGCCCACAAAGAUUUCGCUUUUCACUUAUUACUCAUCAAACUGACUCUGGUUCACAGUGGAAAAGAGAAGAAAAGCUGAUGGAGAAAUGGCAGUGAAGAAGGAGAACAAAAUGUCAGAGCAAUACUUUUGAGCGACUUAUCCUCUGUUCUGCAAUAUUUGCAAAAGUCAGUCUAUAGACGUGAAGCCAACAGGGACCCUCAGGCCUGUGCAUCAGGAUGGUGGGCUGCCUAAGUCCUCUGGGGACAGCAGUGCCAGAAGGAGUAUUGGACACAGUGACCCGACUGUAUGAGAUGAGAAAAAACAAAAACAGGAGGUCCGCAGUACUGAUGAACUAAUCUGUCACUCACAAGCUCAGGUCUGCAAAAAAAAGAAACGAAGCACUAAACAUGGCCAUAAGAGAUGGAAAUGCAAGUCUUCAUUUCUAAAUGAUAAUCAAACCAACGAUCAGAAACUGAUUAACUGUGUAAUUGAAUUGAAUUGAAAAUCAUCCCAUGAAUAACAAUCCAUCCUACCUUCAAGGGGUUAGGAAGCUAACUACAGGUAAUUGCUAUCAGAAAUCUGAUUUGAUUUCCAAAAAUUGUGUGAAUGAACCAAGUUUCUUCAUCUUGAUAUACUAGGCAGGGAGUUUGUUCUUCCAAGUACUAGACUGCUUAAUUGCUUGCUUGGGGGAGGAGAAAUCCUAGGGGAAAGGCAUAUAUGAGCAAUUUCUACUCUGUGAAGCCAGCGCUGUGUCCUGAGCUGGAUCAUGGCCAGAAACAGAAAAGUCUACUCUUCCCUACAGUGGAAGCAACUGUGGAUAUUUCAUCCUAGGAGUGAAUGAAAAAACCUAAAGCUCAUACUUCAUGGGAAUCUUUCAAUAUUCUGACUGAAAACUGGUUAUUUGCUCCUCCAACCCAAAGCCAUCUAGGAACAGCACUCAGAACAGGAAAAAAAAAAGACAAAAAUAAUAAUUAUUCCAAAACGUAUUUGAGCAGAAACAAACACAAACAUUUGCAUUAUUAAAUGGGCUUGUUCACACCUGCUGAGUAGAUAUAAGACGAUAUUUAAGACAAGAGCUAAAAAAUAAACCAUCCCUUUCUGGUUUUGAGUGACAGCAGAGCAAUAAAAAUUAUUUUCACAUUCUUUUCCCUAUUGUUAGAAGUAAUCAUUUGAGUAAAUACACUUAUCUGUGCUGUAACUAUUGAAAUGAAUCCACUUCAAAUAUGUAUACCACCUUUCUUUUUUAUAUUUCUAGAUAUGGUUUCAAUAUAGACUUUCUGACUUUUAUGGUAUACAUAUAGGACAAUAUUCUAUUCUUCUUUCCUUUUAAAUACUUACUGUUUCAAUUUCAAAUAAAAAAUCAGCAUUCUAGUUUGUACAUUUUAGCACAGAAAUGUUUACAACCUUCAGCACAAUUGCUUUUGUAAUUUACUGACUUGGCAUUUUGAGGCGUUUUUAACAAAUUAUGAGAAAUAACACCUUCAGAAAGCAUGUGACUACUUUGAUGCAACUAUUUACAAUGUAUUCAUAAGAAGUCAUUAACCUGUAGAGUUCUUAGACAUGUGGAACCUUUAACAAUUAUACUAAAGAGUACAUACAAAAUACAGAGCUAUGUAAUAAUAACUAAUUUUAAAUCCUGACAAAUUAGAAGUUAAGCCUACUAUCUGUAAAAAUAUGUCCUGAUUCAUUUUUUUAAGUAUAUACCUGAGCCUUUAAAAAGUAUAUGCCUUUACAAUUGAUUUCCAAUAAACAAUACUGAAUAACAAACU

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

Publications