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Homo sapiens (human) PPP1R14B antisense RNA 1 (PPP1R14B-AS1) URS0000A76754_9606

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PPP1R14B-AS1: PPP1R14B-AS1 is a long non-coding RNA (lncRNA) that has been studied in relation to its role in apoptosis, mitochondrial function, and tumor metastasis [PMC7686783]. PPP1R14B-AS1 knockdown did not affect apoptosis in HepG2 and A549 cells, suggesting that it may not be directly involved in the regulation of cell death [PMC7686783]. However, it has been found to be closely linked to mitochondrial function and tumor metastasis [PMC7686783]. Additionally, upregulation of PPP1R14B-AS1 has been associated with poor overall survival (OS) in various cancers, including liver hepatocellular carcinoma (LIHC) and lung adenocarcinoma (LUAD) [PMC7686783]. These findings suggest that PPP1R14B-AS1 may play a role in the progression and prognosis of different types of cancer [PMC7686783]. Further research is needed to elucidate the specific mechanisms by which PPP1R14B-AS1 influences mitochondrial function and tumor metastasis, as well as its potential as a prognostic marker for cancer patients [PMC7686783].

Genome locations

Gene Ontology annotations

Sequence

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GGCAGCACCGGGCAAACCCACUCCUCCACCCUGCCCCCCGGGGCCUGAGUCACCGUCUGAACAACCAGGGAGUCAUGGGGGUGGAGAAGCAGAGCCCAGAAAGCGGGCUAGCCUGCACGCACGCCAAGAUGGAGCUCCAGGCUAGCCCACAGAACAGCCCAGCCGCAGCCGUCCUACCAGACCAGCACCUUGUAACCACAGUCUAACCCAGCGGGCACCAGGCGAUUGUGAGUGCCACGGGGCUGAGGCCUGCGCCGACCUGGUCUGCUGGUGCUACCAGGCUUGAACAGUCUUCAAAUCCACUGCUAUUAGGCAAAUUACCUGGCUCCCGCUGAACUCCAGCACCUAGAACUAUGUCACACUCGUAGUAGGCCGCUGCAUUGGUUGAACAAAUGAUUUUGAAAGAAUGAAUGUCUUCCUCUGUGCCUGCAUUUCCUCAGAAGGCUGUAACAAAGAUUAAAUAGGAAAAUUCGUGGAAAGUUCAAUAAAAAAAAAAAAA

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Publications