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Homo sapiens (human) non-coding transcript regulating alternative splicing (NTRAS) URS00008E39CF_9606

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NTRAS: NTRAS is a gene that is involved in various cellular processes [PMC9171682]. Silencing NTRAS in endothelial cells does not affect the total mRNA levels of TJP1, indicating that NTRAS does not directly regulate TJP1 expression [PMC9171682]. In silico analysis of the NTRAS sequence revealed the presence of several CA-rich hnRNPL binding motifs, as well as a CA16 repeat sequence near the 3' splice site of intron 2 [PMC9171682]. This CA16 repeat sequence is a prominent hnRNPL binding site [PMC9171682]. In conclusion, this study provides insights into the role of NTRAS in endothelial cells and its potential interaction with hnRNPL. It highlights that silencing NTRAS does not directly affect TJP1 expression and identifies a prominent hnRNPL binding site in the NTRAS sequence [PMC9171682]. Further research is needed to fully understand the functional significance of this interaction and its implications in cellular processes.

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Gene Ontology annotations

Sequence

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GUCCCAACCCUGGCCAUGGCUGACAAGGGGCCCAGGGACACUGGAGCAGAGAGACCUGCUGGUCCUUGGGGUUUCUUGCAAGGCUGAUAGCGGGGGAACCUCUCUCACAGGGCUGCUACAAAGAUUGCAUGAGAUUUUGCUCAACAAAUAUUAGCUGUUGGCUCCAGAGUUUAAUACCUCUGAUCACUACAAGCUUUGAAGGCAAGAUAAAAUAACUUCAACAUAGUGAAUCAUCUGUGAACACUUCCUGUGAACGUGUGACUAUGAUUAUGGAACACUCUGUUGCAUCAAGAUGGCCAGAGAUUGUCUCAGAGUCCAGGCAGUGGGAGGAGGGGGGAUUUGUUUCCUGGCUGGGUGGUCGUAGGGCAUCAAGGGAUGAGCAGCUUUGGUUGUCUGGGAUUUCAGCAGCUUGAGGGGAGCUGUAGGGCCCCAGAGCUGUCGCUGUGGCUGUGGUGUCAGAAAUGUAAGCAAGGUGCCUCCAUGGAGGUUAGCGAGGGUGCCCCUCUGAAUGCCGGGUGGAAUGCAACCUUUCGCAUGGAGGAGGCCCUCAGCAGCUGACCUCUGUCUUCCCUGUGUAGAGGGAGGGAGGCUGAGGCUGGGGCUGAGCGAGGGGUAAAGUAAGCCACGUGUCUCAUCAGCUAGCCUGCAGCAAGCACAGCCCUCUGGGAGGGCUGGUUCUAUCCUCCUCCUUGGUGUGAAAUCCAUCAAUCUAAUAGGGAUCCUUAUUUUCCCAGCCACCAAGUCACAAUGAGCAAUAAUCUCUUCUUGUUGGUGCAUAUAAAUUUGCUUCAUUCUUUUUUAAAAAAAAAAAAAAA

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Publications