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Homo sapiens (human) MIR34A host gene (MIR34AHG) URS00008E39B8_9606

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MIR34AHG: MIR34AHG is a long non-coding RNA (lncRNA) that has been identified as an independent prognostic factor and used in a predictive risk model [PMC9110831]. It has also been associated with the heterogeneity of immune cell infiltration, along with NIFK-AS1 and LINC01215 [PMC9641048]. MIR34AHG is part of a ceRNA regulatory network that includes 8 lncRNAs and 4 miRNAs [PMC7052009]. The expression of MIR34AHG exons is positively correlated with the expression of miR-34a-5p miRNA [PMC9688839]. The rs2666433 polymorphism, located upstream to the MIR34A gene and within the first intron of MIR34AHG, has been identified [PMC8584584]. The expression of MIR34AHG is regulated by p53, and its activation leads to increased expression of pri-miR-34a/miR-34a [PMC8038077]. It is also hypothesized that p53 regulates the expression of miPEP133 through the MIR34AHG promoter [PMC7489042]. In summary, MIR34AHG is an lncRNA that plays a role in prognostic prediction models and immune cell infiltration in cancer. It is part of a ceRNA regulatory network involving multiple lncRNAs and miRNAs. The rs2666433 polymorphism within its gene locus has been identified. Its expression is regulated by p53, which also affects the expression of pri-miR-34a/miR-34a. Additionally, there may be regulatory interactions between p53, miPEP133, and the promoter region of MIR34AHG.

Genome locations

Gene Ontology annotations

Sequence

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AUGCGCCCUGCCUGGCCCCCACCUGGUCCUCUUUCCUUUUCAGGUGGAGGAGAUGCCGCUGUCCCGUCGGUCUGGGGACAGCCCAGCUCCCCGGAUCCCGGGCUGGAGAGACGCGUCGCGGCCCCGGGGCCUGGUGGCACGAGCAGGAAGGAGGACCCGGCGGCGGGCUCUGCCUGGGCUUGCCUGGGCUUGUUCCGAGCCGGGCUGCUUCUCGGUGACCACGCAGAUCGGGGGCAUUUGGAGAUUUUGCGGGAGUCCUGCAGCCAAGCUCCGGGGCAGGAGAGGCCUGGAAGCCUGCACUACCUGCUCGCCCCGUCCCAGCAUGCACCCAGGUGCUGGGGAGAGGCAGGACAGGCCUGUCCCCCGAGUCCCCUCCGGAUGCCGUGGACCGGCCAGCUGUGAGUGUUUCUUUGGCAGUGUCUUAGCUGGUUGUUGUGAGCAAUAGUAAGGAAGCAAUCAGCAAGUAUACUGCCCUAGAAGUGCUGCACGUUGUGGGGCCCAAGAGGGAAGAUGAAGCGAGAGAUGCCCAGACCAGUGGGAGACGCCAGGACUUCGGAAGCUCUUCUGCGCCACGGUGGGUGGUGAGGGCGGCUGGGAAAGUGAGCUCCAGGGCCCCAGGAGCAGCCUGCUCGUGGGUGCGGAAGGAAAAAGGCACAGGGGCUUGGUGUGGGCGGCUUUUGGCUGGGAGAAGUUUGCACGUAGGGAGAAUAGUAGCCAGUGUUUGCAGAGCACUUACUAUGCAGGAAGGCCUGUCCUAAGUAUUGUAAGUGUAUUACAUCAUGUACAAGUGUCUGUGAUUAACCCCGUCUUGCAGAGAAGGAAACAAAAGUACAAACAGAAAAUGUAACUAAGCAUGCAAUUAAUAAAAAGGGACCAGGUUUUGAACGCGAGCAAUCUGGCUCAAGAAUCUGCGCCCAACCACCGGCUCCUGUUCUUAGAGAUGAACGUGGAGUCCUGGAGACUGCUCAACAUUGUGACUUGACUGUGAGCGUACGCGCUCCCUGUCCCCAGGAGACAGAUUUCCAGUGCAAUCAUAGAAAGUGCCUGUGUGGGCUUCGGGAGAUGUGUCUGCCUUGGGGAGAAUUUUCCUUUUCAGCUAGAGCCAGGCCCAGGAUGUUGACGUCAGUGAGACGCUGGUGACGUUCUCUGCUCCAGUGGCUGAUGAGAAAAGUUCCUCCAAGCCAGCUCAGUUGAGAAGAAUUAAGUUCUCUGGGUCCCACUGGCUUCACCUACAGAUGCCAACUUUGAGGCCAGUGAACUGUGAGGCCAGCUGGGCUGAUUGCCAUGGCAACAGGAAUUGGACCAAAGUCACCGGAGGAUGGAGAGGGAAGACACAGUGGUGGCUUCCCCAGGUCUUGGACCACAAGGCACAGCCGUGGCCUCCAGGAACCCUGAGAUAACCCGUUAGUGGGUCCUGCACUCCAACAGAGCUCAUGCAAUCAGCCUCUGGUCCUCACCCUCCUCCCAUUGGUGUCGUUGUGCUCUCUAACAUUGACAUUGAGCAGUGAGUGCUCCAGAUCUUGUUCCACUGAUUUUUUCCACUGUUCUCCAGUCUAGCACUUUCUGAAAUUCAUCCAAGCCUAAGAGGUGACGCCAAACGUAAGUGUCUUACACCUCGGACCCCAUGGACUAAGACAAGCCUCUGGGGUCCAUGUGGCACCAAGGAUGGGGCCUUCUAGUACCUUUCACACAGGCCAGGGACAGCACCUGCUGCGACCCCCACCCCCAGCCUCUGCUGCUUCUCCCGUUGCCCUUCCAGCCACUGCCCUGGGCACCUCCCCUGCUCCCGCCUCCCUGCCUGGGCCCAUCUUUCUUUGCACCUCACCAAUUGCGGGGCUUCCUAGUGCUGGAGGGGAAGGGAGCCUGCUUCCAUUCUCACCACUCUGAAAGAAGACCCUGCAGAGAGGUUUUCUGGAAUUUGGAGCCUAACCUUGGCCUUGACACAGUCCAGAUGAGAAGGCCGUCCCCCAGUUAAGCCAGCCCUCCCUCCCUCUCAAUGCUGGAGAGGAAACCAGGCAGCUGGUUGCUUCAGCAAACCCCCUCCCUAUGGGAAUUGUCCUUUUCUUCCUCAAAUAGACUGGAGUGCAGAGGACUUGCUUCAGAGAGAGCCCCUUUGUAACGCACAUUGCACGGGCCGUGCCCCAUGCCCACUCUGCCACAAACUCCCCUCAGCUGCCCAGCCCCGUGGAGCCAGGCGUGGGCUGAAGUGGGGCCAAUGAAAUGCCUGGAAUGCCAGCCGCAGUGACAGGCCAGCACUCAGAUGCCUCUCGGGAGUUCUGACCGAAGCAGCACUGAGGACUGCUUCAGAGCAGAAGUCUACGCCAUUUUCCCCAGUUCUAGGCAGAAGUAAAGAAUGUCUCUACCUUCUCCCAACCAGCAAUUGAUUCAGAGUCCUGAGCUUUUAAAUUAAAGGGACCCCUCUGUUGCUUUAUGCAGUAGCCAGCUUAUUCAUUUGAGUUCAGGUGAAAUCAUUUUCAAGUAACCUCUUCCUAUCCAGCUUUACUUUUAGUUAUGCUGACAUAAAAACAAUAAAAAUUGUCCUCCUCAGAGUUCACCUGUAAAAGUUCCUGGAUAAUUAGUAAGGAAACAGAAAGAGCAGAUAGUUGUUGCUUCAGAUAAAAGUGAUGUCUGGGUUGGGCACGGUGGCGCAUGCCUGUAAUCCCAGCACUUGGGGAGGCCCAGGUGGAUGGAUCCCUUGAGCUCAGGAGUUUCAGACCAGCCUGGGCAACAUCUCUACAAAAAAUACAAAAAUUAGCCAGGCAUAGUGGCAGGACUGUAGUCCCAGCUACUCAGGAGGCUGAGGUCAGGGGAUGGCUUGAGCCCAGGAGGCACAGAUUGAAGUGAGCUGAGAUUGCGCCACUGUAUUCCAGCCUAGGUGACAGAGCCAGACCCUGUCUCAAAUUAAAAAAAACUCUUUGUGGUCAUUUAAUUUACUUCUGCAUUCUUUUUUUUUUUUUUUUGAAAUGGGCAGUGGUACCAUCUCAGCUCACUGCAACCUCUGCCUUGGGGGUUCAAGUGAUUCUCCUGCCUCAGCCUCCCGAGUAGCUGGGAUUACAGGCACCCGCCACCACGCCCAGCUAAUUUUUGUAUUUUUAGUAGAGACGGGGCUUUGCCAUGUUGACCAGGCUGGACUCAAACUCCUGACCUCAGGUGAUCCGCCCACCUCGGCCUCCCAAAGCACUGGGAUUACAGGAAUGAGCCACUGCACUCGGCCUACUUCUGCAUUCCUUAGAGUACAUCCUAGCUAGGAUAUAUUCACUUGUCUUUAGAGCUAACAGCAGAAGAAAGGUACCUAGAUGCUUAUCUAGCUCUUUAUCUUUCUAGAAAUUCUAGAAGAUGAGAGGGGCAGUGGUGGCUCCAAGGGAGUGAUUUUAGGAUGGACUGGGACAGAGAGGGGCUGCUUACACAUACUCACACAGAGGCCAUUAAUUUAGGGAGUUCAAGGUCCAGGAGGUUGACGGCAUCUAGGCCUGUGGCAGAGUGCACUCCUGCUUUGGGGAAUGUAUGGGCAGCUUCUUGCCUGUAGUUGGAGGGUUAGAGAGAGGGAUCAAUAAUUUCAUGGUUGGACUUGAGUUUGGAGCGAGUGGAGUUAGAUACAAAUUCUAUGUUUUUGGAGAAAGUAUUUGAUCUUCUUGGCUGUGAGGCAAAGCGAGGUUUAAAAAUAUUUUUCACUUAAAAAUAUAUAUAUAUGCAUGUAUAUUUAAUACUGUCUAUGGAUUGUGCCAAUAUCUAUUUCAUGGUUUUGAUAUUGUGUAGUUAUACAAGGAGUUACCACUGAACGAAACUGGGGGAAGGGUACACAGAAUCUCUGUACUUUUUUUGUUGUUGUUGCAAUUUCCUGUAAAUCUAUGAUUAUUUUAAAAUAAAAAAGUUAAAGCAUACGUAUUUACAUUUGAUUAAAUGCAGUGUGAUAUCCUGGGUUGGAUUUUGGAACAAAACAAGGCAUGAGUGAAAAAACUGGUAAAAUCCAAAAAAGCCUUUAGUUAAAAGUAAUACCAGUGUUAAUUUCUUAGUUUUGACAAAUGUGCCAUGGCUGUGUAAGAUGCAAAUGUUAGAGGAAACUGGGCGAAGAAUUUGAGGGAACUCUCUGUACUAUUCUUUGCAGCUUUUCUGUAAAUCUACAAUUAUUCCAAAAUAAAAGUCUAUUAAAAAUGUAAAAAAAAAAAAAAAAAA

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