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Homo sapiens (human) long intergenic non-protein coding RNA 1842 (LINC01842) URS00008C0A78_9606

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LINC01842: LINC01842 is a long non-coding RNA (lncRNA) that has been identified as a candidate for a lncRNA signature in glioma [PMC9568296]. It is one of the high-risk lncRNAs that are significantly upregulated in glioma and positively correlated with its progression [PMC9568296]. In addition to glioma, LINC01842 has also been found to be upregulated in lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) tissues [PMC6842565]. It is considered one of the key lncRNAs in LUAD and is involved in lncRNA-miRNA-mRNA cross-talks [PMC6842565]. LINC01842, along with two other lncRNAs (CASC8 and VPS9D1-AS1), has been shown to be significantly upregulated in LUAD and associated with poorer prognosis [PMC6842565]. Functional annotation analyses have revealed potential biological functions of LINC01842, including its involvement in ceRNA networks and its interaction with specific miRNAs [PMC6842565]. Furthermore, LINC01842 has been identified as one of the lncRNAs associated with recurrence-free survival (RFS) in cancer patients [PMC7108035]. It has also been reported to have a critical role in the tumorigenesis of cancers harboring KRAS mutation, along with other hub genes and lncRNAs [PMC9106686].

Genome locations

Gene Ontology annotations

Sequence

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CCGGGCUCGGCUCACCCUCCCCGGAUGCCGCUCCUCCUCCAUCCCCAGAAGUUUCAGCCACUGAGAUUCCCCUUGUCCCGGAGGCUGGAGGGGAAGACCCAGGCGGCUGCGCUUUGGAGGCUGGACCAUCGUGGGGCUUGUCUGUGCCCACUUUUCCCCCAUUCAAGAGUUACCACUGCCAGGCGCAGUUGCUCAGGCCUGCAAACCCAGCACUUUGGGAUGGCAAGACAGGAGGAUCGCUUGAGCCCAGGAGCUUGAGAACAGCCUGGACAACAUGAGCCAGCCAGGCCCCUGGGCCUGGAGCAUCCACAGGAGGAAAGUACAAGAACCCUGGCACCCUGCCAAGCAGCAGGGAUUCUUCAGACACCCAAGGGCUGGUUUGCUGGGAAGGACUCAUGUGACCAGAAGGGGAAACUGAGGCACUGCUGAGCACCAACAGUCCUGGAGAGCUUUAAGAAUGGUUGCCAUCUGAGGCCAGGCAUGGUGGUUUAUGCCUGUAAUCCCAGCACUUUGGGAGGCCAAGGCAGGCAAAUCACUUGAGGUCAGGAGUUCGAGGCUGUCAGGCCUCUGAGCCCAAGCUAAGCCAUCAUAUCCCCUGUGACCUGCAUAUACAUCCAGAUGGCCUGAAGCAACUGAAGAUCCACAAAAGAAGUGAAAAUAGCCAGUUCCUCCUUAACUGAUGACAUCCCACCAUCGUGAUUUGUUCCUGCCCAACCCUAACUGUUCAACUGACUUUGUGACAAUAUACCCUCCCCGCCCUUGCAAAAAAAAAAAAAAAAAA

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