Homo sapiens (human) p53 regulation associated lncRNA (PRAL)

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Homo sapiens (human) p53 regulation associated lncRNA (PRAL) URS00008BAAAE_9606

3,286 nucleotides
7 databases (EVlncRNAs, GeneCards, HGNC, LncBook, LNCipedia, MalaCards, NONCODE)
Found in 0 other species
55 publications
1. lncRNA
2. antisense lncRNA

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PRAL: PRAL, or Potential Renal Acid Load, is a measure used to assess the acidifying potential of a person's diet. In a study, it was found that children with higher PRAL scores had significantly higher levels of EBC miR-133a-3p before adjustment. The odds ratio was 2.52 with a 95% confidence interval of 1.30 to 4.86, and the p-value was 0.006 [PMC8949211]. The expression of LCN2, a gene, was found to be the most drastically and consistently altered in the study [PMC10007849]. On the other hand, TNFSF18 displayed very low and variable expression [PMC10007849]. The expression trends of PRAL differed at both the sequence and mRNA levels [PMC10007849]. These findings suggest that PRAL scores may have an impact on EBC miR-133a-3p levels in children and that LCN2 expression is significantly affected by PRAL scores. However, further research is needed to understand the exact mechanisms underlying these associations and to explore potential interventions or dietary modifications that may help mitigate any negative effects [PMC8949211] [PMC10007849].

Genome locations

Gene Ontology annotations

Sequence

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AAACCUGCAGUUGCCUGGUCAGUGGAUCCCAUGUGCAGAGGGCGAGACGGGGCCCUGGCCAGGCGUUGGGAGGCGGGAGGCUCGGCCGGCGCUCCGGGUGAGGAUGGCACGCCCCCGCCCUUGCUUCUGCGCACAGGGAAGACAUUCGGCCCCGAACUUGGGGCUCAAAACGGUUCAGUUCGCUGCCUUUCCCAUCCUGACCCAGCCCCGGGUUUUUUCCGAAGCCGCCGCUGGAUAGGUUGCAUUACUAGGCUUCCCCCAGCCACUCUCCCUGCCCAAAGCCUUCAGAAGCCGCCCCUCUCCCCUUCACCUGGCCCUUAUCCACUGUCCCAGCCUCAUUUCUUUCCCCCUCCCUGAAUGUCUUCUGCUCCCCUUUCCUUGGGCACUGCCCUUAUCCUGGGGUCCUGGCUGCUGCCAUUCCUGGCCCUGGAAAACCAGUGCGGAACCCAAAGAAAGGUGGAAGAGCAGCUUUUAGAGAGGUGUUUUUAUUCUUUGGGGACAAAGCCGGGUUCUGUGGGUGUAGGAUUCUCCAGGUUCUCCAGGCUGUAGGGCCCAGAGGCUUAAUCAGAAUUUUCAGACAAAACUGGAACCUUUCUUUUUUCCCGUUGGUUUAUUUGUAGUCCUUGGGCAAACCAAUGUCUUUGUUCGAAAGAGGGAAAAUAAUCCAAACGUUUUUCUUUUAACUUUUUUUUUAGGUUCAGGGGCACAUGUGUAGGCUUGCUAUAUAGGUAAAUUGCAUGUCACCAGGGUUUGUUGUACAGAUUAUUUCAUCAUCCAGAUAAAAAGCAUAGUACCAGAUAGGUAGUUUUUUGAUCCUCACCCUCCUUCCAUGCUCCGACCUCAGGUAGGCCCCAGUGUCUGCGGUUCCCUUCUUUGUAUCCAUGUGUACUCAAUGUUUAGCUUCUACUUAUAAGUGAGAACAUGUGGUAUUUGGUUUUCUGUUUCUGAGUGAGUUCAUUUAGGAUAAUGGCUUCCAGCUCCAUCCACGUUGCUGCACAGGACAUGAUCCCAUUCUUUUUUAUGGCUGCAUAGUAUUCCAUGGUGUAUAUGUGCCACAUUUUCUUUUUUUUUUUUUUAAGGCAGAGUCUCGCUUGGUUGCCCAGGCUGGAGUGCAGUGGCAGGAUCUCGGCUCACUGCAACCACCACCUUCCAGGUUCAAGCGAUUCUCACGCCUAGGCCUCCCAAGUAGCUGGGAUGACAGGUGCUCGCCACCACGCCUGGCUAAUUUUCGUAUUUUUAGCGGAGACGGAGUUUCUCCAUGUUGGCCAGGCUGGUCUCAAACUCCUGACCUCAGGUGAACCACCCGCCUCAGCCUCCCAAAGUGCUGGGAUUACAGACAUGAGCCACCACUCCCUGCCACCACAUUUUCUUUAUCCUUUCUACCACUGAUGGACAUUUAGUUUGAUUCCCUGACUUUGCGAUUGUGUAUAGUGCUGCCGUGAACAUUUGUGUAUAUAUGUCUUUAUGACAGAAUGAUUUAGAUUCCUUUGGGUAUAUAACCAAUAAUGGGAUUGCUGAGUCAAAUGGUAAUUCUGUUUAAUCAUGUCCCAUUUGUCAAUUUUUGCUUUCGUUACAAUUAUUUUUGGGAUCUUUGUCAUGAAAUCUUUUUCCGUUCCUAUGUCCAGAAUGGUAUUGCCUAGGUUAUCUUCCAGAGUUUUUAUAGUUUGGGGUUUUACAUUUAAGUCUUUAAUCCAUCUUGAGUUGAUUUUUGCAUAUGGUGUAAGGAAGUGGUUCAGUUUCAAUCCUCUGCAUAUGGCUAGCUAGUUAUCCCAGUACCACUUACUGAAUGGGGAAUUCUUUCCCCAUUGCGUAUUUUUGUCAACUUUGUCAAAGAUUAGAUGGUUGUAGGUGUGUAGCUUUAUUUCUGGGCCCUCUAUUCUGUUCCAUUGAUCUAUGUGUCUGCUUUUGUACCAGCACCAUGCUUUUGUACCAGUAUCAUGCAGUUUUGGUUACUGUAGCCCUGUAGUAUAGUUUGAAGUUGGGUAAUGCGAUGCCUCCAGCUUUGUUCUUUUUGCUUAGGAUUGCUUUGGCUUUUUGGGCUCUUUUUUGGUUUCAAAUAAAUUUUAAUGCUUUUUUUUUCUGAUUCUGUGAAGAAUGUUAUUGGUAGUUUGAUAGGAAUAGCAUUGAAUCUAUAAAUUGCUUUGGGUAGUAUGGCCAUUUUAACAAUAUUGAUUCUUCCUAUCCAUAAGUAUGGAAUGUUUUUCCAUUUGUGUCAUCUCUGAUUUCUUUCAGCAGUGUUUUGUAAUUUUUGUUGUAGAGAUCUUUCAUCUCCCUGGUUAGCUGUAUUCCUAGGUAUUUUAUUCUUUUUGUGGCAAUUGUGAAUAGGAUUGCAUUCUUGAUUUGGCUCUCAGCUUGGAUGUCGUUGGUGUAUAAAAAUGCUACCAUAUUUUGUAUAUUGAUUUUGUCUCCUGAAAGUUAGCUGAAGUUGUUUAUCAGAUCUAGGAGCUUUUGGGCCAAGAUCAUGGGGUUUUCUAGAUAUAGAAUCAUAUCGUCUGCAAACAGAGAUACUUCGACUUCCUUUCUUUUUGGUUGCCUUUUAUUUCUUUCUCUUGCCUGAUUGCUGUGGCGAGGACUUCCAGUACUAUGUUGAAUAGGACUGAAGUGCCUUGUUCUACUUCUCAAGAGUAAUGCUCCAGCUUUUGCUCAUUCAGUAUGAUGUUGGCUGUGGUUUUGUCAUAGAUGGCUCUUAUUAUUUUGAGGUAUGUUCCUUCGACGCCUGGUUUGUUGAGGGUUUUUAACAUGAAGUCAAGUUGAAUUUUAUCAAAAGCCUUUUCUGUAUCUAUUGAGAUGAUACGUGAGUUUUGUUUUUAGUUCUGCCAAACCUUUUCUUUUAAAGCCCAACGAAUAAAACCCAUCACCUUUCACAAGACCACCACAGCAAGUAGGCAGGAAUGCCAGUGUUAAAAGUGAAAUCUUUUGAAUUUGUAGUACCUUUCCUUUUCCAAAUCUAGCUGAAAUUUCUCACUUGUUUUCCUUUUGAUGAAGCUAACCACCGGCAUUUCUCCUAAGAAAUGGAUAUAAAAAAAGUUUGAUAUGGUUAAAGUAAGAAGUGCUAGCUCCUAGAAUAUCUCUGGAUAUUGCUGUCCCUUGUUACAGAGCAUGAGCCCUGCCCAAAGACUGGAGUGUAAUGGCAUAGAAAAGGUCAGGAGCCCACUGAGCCAGAAGUAUAGGAGGCUUGCGACAAAGUUUAACAGGGGCCUGUUGCUAUCACUGGGUGGAGGGACAGAUGGGAGAACACUCACACCAUGGAAUCUUAGGCAGCCAUUAAUAAAAAUAAGCCACACUG

Taxonomic tree

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Publications