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Homo sapiens (human) PROX1 antisense RNA 1 (PROX1-AS1) URS0000812192_9606

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PROX1-AS1: PROX1-AS1 is a long non-coding RNA (lncRNA) that has been studied in the context of lung cancer. In one study, the knockdown of PROX1-AS1 was found to significantly inhibit the growth and mobility of lung cancer cells [PMC10072212]. Another study analyzed the association between PROX1-AS1 expression and overall survival rate in lung cancer patients, and found that higher expression of PROX1-AS1 was related to a lower survival rate [PMC7989960]. Additionally, PROX1-AS1 was found to be enriched in cells transfected with biotinylated miR-211-5p, suggesting a potential interaction between PROX1-AS1 and miR-211-5p [PMC8806442]. The clinical value of lncRNA MIR193BHG, PROX1-AS1, and GATA3-AS1 in the diagnosis of early-onset preeclampsia (EOPE) was also assessed using ROC curves [PMC7293732]. These findings highlight the potential role of PROX1-AS1 in lung cancer progression and its association with patient outcomes. Further research is needed to fully understand the mechanisms underlying its function and its potential as a diagnostic or therapeutic target.

Genome locations

Gene Ontology annotations

Sequence

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ACAGUUGAGGCUGGGAGCAGAAAUAAUCAACAUGCCCAUUAGAUACAGGACGGAAUAAUGCUUCUAUUGGUUGGGUCCCUUCGAGAGAGAACCAUUCUCUGCUUUCAAUAGGACAGAAGAGCUCCUUGGCACUGGAUGCCUCCGGGUCUGGUUGAGAGAGGAAUGGUUAGGAGACUGUUCUGAGGAUACGCAGACAUCAUCCAAAGCUUCCUACAUUCAGAUGAGGACAGAGGUUGGGCCAGAGCUUUGUAAGCUUGUUACCUAAGGAUGGUUCUGACCAUGUAAGCAGAUCACAGAAGCUGGAGGCAAAGGAUGCCAAGAUGGGAAAGCCACAUAAUGGAAGGAUCCUGGAUUUCAGAGCUGUCACUUGGAGGAGGGGCACCCAGUGAAGGUGUCUUAUCUAACCCACACCAUAUCUUCAUGAAGUGGCCAUAUGGAUUUGAUCCCUAUCCUUCAGAGGUGCUCAGCCUAAGGGAACACGGAUAGUAGAUUAAGCACUGACCAGAGCCAGCCUUGACAAUGUGCUGAUGGCAACCUAGAACAUAAGCAGAGGAGUAUACAGGACAAGAACUUGAUGGUCUCGGGAAAAUGGACAACAUGACUCAGGUGAAAAAGAUUGAUCAUCAGAUGUUUCUUAUGUAUCAACCUGAUAUUUAAAUCCAUGAAGGACAGAGACGACAAAGGCAGGUGGAAUAGAUAGAGAAGAGAUUCAAGGUCUGAGCUCUACAUUACUCAAACUGUUAGAGAUUAGGAAGAAGAGGAAGACCUGGCAAAAGAAUGUCCUGGGAUGUAGAAAGAAAACCAGAAGCUUGUGUUCUCUGGAAACCAAAUGAAGAAAGGGCUUCCAGAAGGACAGACAAAGUGUAGUGUGUCAAAGGCUCCUGAGCAAUCAGAGGAGAGCACAAAGGGGCUCACAGGACUUUGGUAUCUGGAUCACCCAGUGACACUUCCUGAUCACGAGAAACUGUCAGACCAACAGGGGCACUUUCUGAAACCAGCAGUUCUUCAGUGCCCAAAUGCAACCUUGAUGGUUUGAUUUUGGAGGAUGGCAAUUCAUUAACAGCACUCCCCAGUGAUAAAUAUGAAAACCAAUAAAACCCCCCACCCAAGGCAAUCUCUCCCAGCUCCUCGCUUUGAGUAAAGUGAGUAACCUCCAUUUCUGCCAACUCCUGUCUUGUCUGAAGCCACAUUUCCCCAGCAAUGUCACAUAUGCAUUUCUUGAUCCUGGUCAUUUCUCCUCUUGGGAGAUGAAUCAUAAAGAAAAUGAGAUCUGUGUGCCCUGGUGACUAUGGAUGCAAGAGUCUGCUGCCCUGGAGGGAACAGCUGGAAAAGUAGAUGGUGAAGACGUGUGGGGGGGAAACAGUGGAGAAGGCAUCUUUGCAGGGGAUCAAGGUGACAGAGUGAUUAGUUACACUGUUUUGACAUGUGAGAACAGGGGGUUAUAAAAAUGGAUACAGGAAGAGGGAGAGAAAGUAAGGACCAAAACAUGAAGCCAGUCAUGAAUGUUUUUACAUAAAAAGCAGCAGAUUUACGGCAAAUAUGUGAUGUUUCCACAUUUUCUGCCUCUAGUUAGCAGGGGCAGCACAAAGAGCAUUACUGUGGAGCUGAACUUUGGGUAAAAGAUUAACAGCCAGUCCUUUCUCUCCAGUGUCUGCUUCCUUCUGGGCUUGCCCUGGGGGAAAAGGAGGGCUGGCAUGGAUAUGCCUGCAGCCCUCACCCUAGAUGUUCUUCCACGCCUCUCUGUUCAUUCAUUGCUUAGUCAUUCCUCAGGCAUGGAUUGAGACCACUGUGUGCCCAGGACCGACCUGGCCUAGGAUGGACAUAGAGAUGGAAAAGGCACAGGGAGCAGGUGACAGAGACAAAUCAAGGUCAUGGAGAAUAGCAGAGUAAGAUAGAAGAUGAAGGCAGGAGAUGGGGUUCUUGAGAAAGCGAGAGCAGGACUGACCCGUGUCUGCCUCACCUGUUAUUGCUGUAGCCUCUUCUCCUUGGAGUAUCCCUCCUGCUCUUGCAUCACCUUAGGAACUUGGAUCAGAGAGGAAAGUUACGGCCUGGAUAUGUUGUAGUAGGAGGGGACAAACAUGUUUGGAGACAGAAAUGCUUGGGGAGCGGGUGUUUUUGGGGGAUGAGACUUUCCAGGUCUCUCAAUUCACACUAUGUAGGUAGUUCACUGCACAGCUUAAAUAAGAGACAACUCUCCGGAGUGGUUGGCUCUCAUCCAAAAAAUGUGUUUUGGGCCUCAGAUUUCCAACGGAAGGGCUGAAGCGUGACUGGCCUGAUGUCAACUACUGAAGUCCACCUGCCCCUGCCCUAUCAGGUGUGGAAAUGCUGGGGUUCCUCUCUCAGAACCUACUUCCUGAGAUGUCGAAAUAUACCCAAGAGUAUUUCUGGGCCUUCUCCAAUCCGAAACUGUUUAGUUUUUGUGUGUGUGUGCCUACUUGGCCACACUAGAAGACAGAGGUGGCCUGGGUGAAAUGCAGGUUUCUAGAGGCUCUCUGACAAAGCUCAGGCCACCAGCCCCAGGCCAGCCUGUGGGUAGUCCUGGCUGACAGUCACUUCAUACCUCACCUGGGCUUUUUGCCAAAUUCAAAGUGUGUGUAUAUGUGGAGUGCUGGGUUCCCACCACUGACAGUCUGUAAGUCAUUCACUUAGCUCAAUUUGUCUUACUUUCUUCUGAAAUUUCUUCCUUCUUGUUCUUUUUCCCAGGAGAAACCAGGAGAAGGCAGUCCUAGGGCAGUCUCCGGGCCAGCUUUCCCUAAUAAGAAGGCAGAGCUCCUCUUCACCCAGACUUCAGACCUAUAGAGGCAGCCUGGGGUCCCGGGAUGCCCUUGCACUCAGAGAUGUCCCCAGAGUCCUAGGGAAAUGGAGGAUAACUAGGAGGAAGCUGUUCAUGGCUGGCGAUGAGGUCUAUACCUUCUUGUCCGUCUCAGUGCUGUCUGCUAUUGAAUUUUUGUGCAGAUCACAUUAACUUAAAGCCAGUUCUCAAGAAGCUCCCCCUGCCGCCGGCAUAUCCACCAGUUGCUCCCCUUUCCUGCCAUUAAUCAGGGUCUGCUAGUUAGAGAACAAAUUCCUAUUUGUCCAAACAGUUGCCAACACCCCCACCCCAAGGUAGUUAAAUGAGGAUGAAUGGGUCAUUCUUAUUAAAAAAUGACUUAAAUUUCUCAAAUUCUAUUUAUGUUUCUUUUACAUCCCAAUUUUCUAUAGAUUUAGUGACUCCAAAUGAUAAGGUCUCAAGCUCAUAAUAAUUUAUCCCUUGGGUAACACACAAGGCUUGGUGGUAUUUCAGUAAUAUUCAUGACAACAGCAGCUGUCGUGCUAAUAAGGACUGAUGUCACCAGAGCACUUUCUAUGUGCCAAGCAUGGUGCACAACACUUUACAUACAUUAUGUCAUUUAAUUUUCA

Taxonomic tree

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Publications