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Homo sapiens (human) long intergenic non-protein coding RNA 1411 (LINC01411) URS00007E506F_9606

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LINC01411: LINC01411 is a long intergenic non-protein-coding RNA that has been found to be upregulated in various studies. It has been identified as a potential regulator of PPARG in trans, along with another lncRNA called TENM3-AS1 [PMC9239745]. LINC01411 has been reported to be the most upregulated lncRNA in the study of lncRNA in osteoarthritis [PMC9239745]. It has also been identified as one of the lncRNAs with elevated expression variation and low AUC, making it not a good model [PMC7199595]. LINC01411 is part of an 8-lncRNA signature that has been developed as a prognostic biomarker for colorectal cancer [PMC9509511]. It has also been found to be differentially expressed in both subchondral bone and articular cartilage in osteoarthritis [PMC9258540]. In addition, LINC01411 is among the top-ranked age-related macular degeneration genes, suggesting its involvement in disease progression [PMC10148661]. It is one of the most significantly upregulated lncRNAs in hip and knee osteoarthritis [PMC7702083]. Although some differentially expressed lncRNAs associated with osteoarthritis have been previously identified, LINC01411 and AC100782.1 have not previously been associated with the disease [PMC7702083].

Genome locations

Gene Ontology annotations

Sequence

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CCUUCCCCAGCUUUGGGGCCACAGAGGGACAGAAACCGCAGGCAGGCUGGCCUGGGAAUGAACCUACACCAGCCUGAAGUCAGAAGAGCCUCUAGGAGCCUCCAGCCUGGACUCUUUUUACAGAUGGGGAAACUGAGUCCCAGAGAGGGAGCAAUGAAGGAUGUCUAAGGUCAUCAGCAACGUAAAGCCAACAGCAUCAUCCUGAGUCAUGUUUGAACCUGAGGGAAAGAAACAUAUGUUCGAAGAGGUUCUGAGGCUGCUGCACCCGAUAUCAUACCUGGUUGGCCCUGGGAAAGGGCCCACCUCCAAUACAUAAACACAACCAGCUUUGACAGUGAGCCCUGAAGCAUGGCAUUGAGAAGCUGCCUAAGAAGGAGGCAGAUCCAUCAGCCUGGGUGCCCGACUGAUUACCCUGAGCAGAGCUCCCCAGCCCACCUGUGAUGGACGCAUGGAGCUUGAGCAAGGAAUAAAUAUUCGUUGCUGGACUCUGAUUACACUGGACCUAUCCAAGAUCUGAGAUCAUCAACUCAUCUCAAAAUCCUUAAGCUGACCACAGCAGCAUCGUCCCUUUUGCAGUGUAAGGGAGCCCAGCUGGGACAAUGUGUGAAUCAACGCAUGAAGGAGUGAGUGAGCAGCUAACCAAAUGAAAGAAUACUCAGAUAUCUGGGGUACAGUUCCCCUCCAGGUUUGCACAGCAUCUGCUGAAGUCUCCACUAGAAACUCAAUGGAAGGUCCCCACCGGAAACUGAAAGUCUCCUAGAGUGGCUUUGAGUUGCGGUUUCACCCUCCCUGCAGAUCCACAGGGGAGGCUGGGGCAGAUGGAAAAUACCAACUUGAUGGUCUGUGGCCACACCAUGCUGCUCCCCAAGGCCCCUCAGAAUUUCACUGCCCAAUAUGGUAGCGCCCAGCCUGAAACGUGGCCAGUGUGAAUUGAGAUGGGCUGGAAAUGCACCAGACUUCCAAGAGCUGGACAAAAACCAUAUACGUAAAGUAUCUUUGUUUUACAUAUUUGUACUGAUGACACAAUGAAAUCAUAUUUAGGGUAUUUUCUGUUACAUAAAAUACAUUACUAAAAUUAAAAAAAAAAAAAAAAAA

Taxonomic tree

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Publications