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Homo sapiens (human) SGMS1 antisense RNA 1 (SGMS1-AS1) URS00007E4E8F_9606

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SGMS1-AS1: SGMS1-AS1 is a long non-coding RNA (lncRNA) that has been implicated in various biological processes and diseases, including immune response modulation, inflammatory response suppression, and leukemogenesis [PMC9716354] [PMC8620399] [PMC9327205]. It has been shown that SGMS1-AS1 is directly activated by BP1 and mainly located in the cytoplasm of different cell types [PMC9327205]. SGMS1-AS1 has been found to interact with miR-181d-5p and SRPK2, suggesting its involvement in RNA-induced silencing complex (RISC) mediated mRNA destabilization or translational repression [PMC9327205]. Furthermore, SGMS1-AS1 has been shown to regulate the growth and epithelial-mesenchymal transition (EMT) progression of lung adenocarcinoma cells through the miR-106a-5p/MYLI9 axis [PMC9213143]. In addition, SGMS1-AS1 has been identified as a potential therapeutic target for lung adenocarcinoma and a protective factor for prostate cancer patients [PMC9763621] [PMC9899836]. It is worth noting that further studies are needed to fully understand the biological functions of SGMS1-AS1 in different diseases and its potential as an independent prognostic factor [PMC8104912] [PMC9470881]

Genome locations

Gene Ontology annotations

Sequence

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AUCUUCCGCCCGGCCAUCGGGCCGCGGGCGCUCGGAACCGACCUGGGAGCUGGCGGGACCGUCCUCCCCCGCCACGCCCUCCCAUCGGGCUUUGGGCGCCGGACUCUGGCCACCGCUCGGCACCUGCCUCCGCCUCGCCUUGGGGUAUAGGAGUCCUGUACCGACCCCUGGCUUGCCCAGAGGACAGGUUCUCGCCCGGGCCAGAAGCAAACUGCGGCGAAAUCGAGACAACAGAACUCAGAGUCACUCUGUCACCCAGGCUGGAGUGCAGUGGCACCAUCACAGCUCCCUGCAGCCUUGACUUACAGGGCUCCAGUGAUCCUCCACCCUCAGCCUCCUGAGUAUCUGAGACCACAGGUGCAAGCCACCAUGCCCAGUUGUAGCAAGGAAACCAAAAGGUAUAAACAUUCACUGAUUGAAAAACAAUGUCAUAAAGUCAUCCCAGUAUCUGUGAGGAGUUGGUUCCAGGACCCCUGAGGACACCAAAAUCCUCAGAUGCUCAAGUCCCUGAUAAAAAAAUAAAAGCAGUGGUGCCCUCGGGUUCAAAAACCUGAACGGUGGUCUUCAGUUGUUCCCCCAAGCUCCUCUAUCAGAGGCCCAGACACUCCAAGAGGCUGGGAAGAGGCAAGUGGCUUUCCCUGACUGGCAUCAGACUCCUGGAUGGCUGUGUUUCUGCAUACUCCACCAUCAACAAUCAGAAGGGCACUGCUUUCUUCAAGAAGGGGACCUUGCAAAGAACUGUCUCAGAUGGACUAUCUUUGAGUUCAUCUUGUUCUGAAUGUGAGUCUGAGUCUUUGUUUCCAGAUGACACAGUGCUGUCUGAGUCCUCUGAAUCACCUGCCUCAGAGCUGCAGCAAAGUUUCUGCUGCCCAGAAACUGAAUGGGCUGCUUGUAAUGCAGAUUCUUCCUCCUGGACAAGAAGUGCUGCUGCUUCUAGUUCUUCCAGUUCUAACCCCAACUGGGCCUUUGUAAGGGAGACUUCCUUUAAGGCUUCUGCAAGAGCUGCCAACGUUUUGGAUUUGACUUUCUGAGUCCACACACAGUAGUAUGAGAUGUAGAGAUCAUUCAGUAUGUAUGCUGGGUCGUUUUCCUGAAAAAUUUUGUGAAUAUCCAGGAGACACUUUAAAACUGCACUUUUACUUAAUUGCAGUAUCUUUAUAGUCUCCCCGUAGGCCUUCAUCGCCAGUUUGAAAUGGCGAUAGAGCAGGUAACACAAUACCCUUCUUCCAAAAGACACCAUGAUAUCAUGAACAUUAGUCCAAGUCUCAAACCAGCAUAGUAUUGGACUCAAGUUUCGUGAUAUUCCAUGCAGAUUCAACGUUCUUGUCUCCUUCAGUGACACGGGUUUCUUAGCAAUAUGCCAGAAGGAUAUCAAUCGAACUGUAGUACACUUGACGACAGGCUCUGUUGUCUAGCAGAUAAGAUUUAUUGACAAAUUCUUGUAGCUGAUAUUUCUCUUCUUCAGAAAAAGACACUAAUGCAGCAUGAUUUUCUUGCUUCUGACUCUUUUCCAAAAAGGCCGUCAUUUUUUAAUAUUUGUCAGUCCACCAAGGAUUAUACUUCAAAAUCUGUUCAACUGCCUCAUCUUCAAAAAAGUCAGCUAGAUAAUGAUCAGGAUCAAACUUGGCCAGCUCGGCGGCCAGGUGCUUUUGUUUUCGUUCUGCUGCAGGGAUGAAAUCUGGAUCCUUAAUAACAUCACUCAAUUCAUCCUGUAACUGCUGAAACACUCCUGAUCGUAAGUUUCCAAACCCAUAGUGGCAUGAGGAUUCAAAGCACUUUCUGUUACCUCUUCAUAGGGUGUCUGCUCAAUUUCCCAAUCAAACUCUUCAUCGUCAACUACUUCCUCAGGAAUUUCAGAAUCACCUAUUGCUUCCACAAGUGGUUUUGCUGUCCCGGAUUUUCCUGGUGCCAGAAGAGCAACACAUGUUCAGCCCCUCAAAAUGCUGGCCAGGGGUUUCUCUGGGCAGGCGAGUGGUAAAAAUUCCUUUAUCUGCAUCAUAGGACCCUUGCUCGCUUCCGUAUCCAUAUUCUACAAUUCUUCCAGGAGGGGUUAAUCUGAGAAAGUACGGCUUGGCAUAGUAGUCUAGGCCGACCCCUCGAAGUAGACGUUGAACUCGGAGGCCGGGGCAUAGGGCACGCGGAUGGCGAUGGUCAGGAAAUCCGGCUCCUGGCUGAGGCUGAACGCCGGGGUCAGCAUCGCGGCACCAGACGCAGGGGCCAGCGCGGCUCGCCCUCGCUGCCGCGGCGGUCCCACCAAGCAACUCUCUCCAAUUUUACCUUUUUAAAAUAAAAGAUGUCUGGGCCAGGCGCAGUGGCUCACGCUUGUAAUCCCAGCACUUUGGGAAGCCGAGGCGGGUGGAUCCUGACCUGAGGUCAGGAGUUCAAGAUCAGCCCCGCCGACAUGACGAAACUCCGUCUCUACUAAAAAUACAAACAUCAGCCGGACGUGGUGGUGGGCGCCUGUAAUCCCCACUACUCGGGAGGCUGAGGCAGGAGAAUCACUUGAACCCGGGAGGCAGAGGUUGCAAUGAGCCGAGAUCAUGCCACUGUACUCCAGCCUGGGUGACAGAGUGAGACUCUGUCUC

Taxonomic tree

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Publications