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Homo sapiens (human) TBX2 antisense RNA 1 (TBX2-AS1) URS00007E4A0B_9606

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TBX2-AS1: TBX2-AS1 is a long non-coding RNA (lncRNA) that is tightly co-expressed with TBX2 and is associated with neuroblastoma [PMC8394133]. In a study, TBX2-AS1 was identified as one of the top ten most important lncRNAs associated with the RF model [PMC9989175]. Furthermore, TBX2-AS1 was found to be upregulated in tumor samples compared to normal samples in neuroblastoma [PMC8394133]. The enrichment of eQTL signals for TBX2-AS1 suggests that variants at this locus may be associated with pulse pressure during cardiac development [PMC9975214]. In the context of renal cell carcinoma (RCC), a risk score was established using a 9-lncRNA signature, and TBX2-AS1 was one of the lncRNAs included in the risk score formula [PMC8806408]. In osteosarcoma, TBX2-AS1 was identified as one of the four important ARLncs used to construct an effective four-lncRNA signature for risk prediction [PMC10076677]. The expression level of TBX2-AS1 varied in different risk subgroups, with lower expression observed in the high-risk group for osteosarcoma [PMC10076677].

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Gene Ontology annotations

Sequence

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CGGCUGCCUGCGCCGGACUGGAGAGCGCGGAGGGCCGACCUGACCCGCCGAAAGGGCCUGAGGCGAGGGGAGCCCGGGUCCCGGGGCCUUGGGGAAGGACCCGCAGCCGCACGCCGGCCCCAAGUGCAAAGCAUUGACACGACCCCGAGCGGAGAGGGGGCGCCCUCCUUCUCCCGCGCCCAGAGGCCCGGCCGCUCUGGCCCGAGCCCCAGCCUGGCCUCCGACCCAGCUCCGGGUCGUGGCGCCGCCUGGGGGUCCCUGCGCCCCGGAAAGAGACAGCAGGCACUGGAAAGCGAGGCCGGUGGGCGGGCGAGUCGGGAGGCUCGGGCGGCCGAGGUCCGGGAGCGGAUCCCAGGUGGCGGGAGCUGGUGAGUGGAGCCAUGGCCGAGCCCUGCUGGGGCCGGCGCGGGCGGGAGCGGGACGCGGCCUUGCGCUGGGGAAACGCGGGGACCCCCUACCCGCGCCCGCCUUCACCGGAAGACUCGGAAGGAACCUGGAGUUCUCCGCAGGCCCGGGCCCCGCCCUGAGCUUUCCAGCGGCCGGGAGGAGCGGAUCCUCGGGGCCAGGAAGGUGCCCUGGCAGGAGGGACUGGCUUAUGCCACCCUGUGCAGGAUCGUCUUCUCAGCUUACAGAGCCUAGUGUGAUUCAACAACCCUCCAUCUCUGCCCCCAACAUGCCCAACUGAUCUGGUGGAGGGAACUGAAGAUGAAGGCCUCUCAGGCACCAUGGAUGGGAUGGGUGUGUGUGAAGGGGGCAGGGUCCCCAGGAGCUGCCCCAGGUCUGGCUGGACAGUUGCACGGGAAGUCCUGUUUGUGAACUCAACGUUUCCACGGCUUUUCCAUUAAACUUUACCCCAAAUCAC

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Publications