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Homo sapiens (human) long intergenic non-protein coding RNA 1376 (LINC01376) URS0000770BFF_9606

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LINC01376: LINC01376 is a long non-coding RNA (lncRNA) that has been identified as one of the most upregulated genes in circulating tumor cells (CTCs) and metastases compared to peripheral blood (PB) [PMC8989945]. It is also upregulated in uterine corpus endometrial carcinoma (UCEC) and positively correlates with HDAC7 [PMC7199595]. In a qualitative analysis, LINC01376 was found to be one of the nine newly identified lncRNAs that were not previously detected in a quantitative analysis [PMC8945364]. In terms of its association with overall survival, LINC01376 was among the 20 lncRNAs significantly associated with OS, with its upregulation indicating its importance in maintaining the tumor environment [PMC9712781]. Additionally, LINC01376 has been found to have single nucleotide polymorphisms associated with breast cancer [PMC7199595]. In a study evaluating the accuracy and specificity of lncRNA markers, LINC01376 was one of the top candidates with high confidence results [PMC7199595]. References: - [PMC8989945]: Supplementary Fig - [PMC8945364]: Not shown by previous quantitative analysis - [PMC9712781]: Figure 2D - [PMC7199595]: Downregulated in tumor; positively correlates with HDAC7; SNPs associated with breast cancer; top candidate marker

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Gene Ontology annotations

Sequence

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AGAAUAUAUAUGUAAUAUAUAGCUUUUUUUUUUUUUUUUACUUUAACAUAUGUUCCCACAUAGCCAAAUGAUUCAACUCAGUACAGUUAACAACUUAGAAAGGGAUUCAUUGAAUUUUCCAGGUCUCUUCAUGGCCAGAGUUGCUUUGUAAGGAGACCCUAAAUGUGGAAUAAUCAACAUGUUAAAGUAAUCUAGAUGUUUAUGAUUUGAUAACUCUUUAGUGCAUUGUUUAACAACAUGUUUUCAAUUUACUUUCCUUCAAAUAGCUCCAAAUAACCCCGUGAUUUUGGAUGAUUGAUUAUGGGAAUGCUGCUUUCACUGUACAUCCAAGCUCUCCUGGCCUCAGCGGAUAAGUAUAUGAGAGCACAGUUUUCCUGGUGUCAGGAUAUGAAGAUCCAGGGAACAAAGAACCUCAAAGAACAACACCUGGAUUGUCAAGGUUUGGCCAGCAGUGCACUUUCUCCAACCUUACAGUCAUACGCAAGUUGUGGUUCUCCUGUCCAGCCUGCCACCACUGGACCAUCCCUGUAUACAUUCCUUCUCCCUUUGAAGAAAUCCACAAAAGAAAAAGCAAAAUACUGACAAGUUUUCAAAGCCAUGAUUUACAGGAAUGAAUUCUGAAAAGCAAGUGGCUAACAUCCGAGUUCAUCAUCAAAUAAUAUUUCUAAAGCACCCUCUAGUGUCUGGCCCCAAGCCAGAUGAUUCAACGCCUGGAGAAGCUACAGACUUUUUAAAAGUAAAAUAGACUCAUGUCUGCUCAUGAGAAGCAAGUCAGCGUCAUUUAGGAUGCCUUAGGAAUGUCUCUCUAAAUAAGGAUUAAAAAUGGAUUGCUGUAGAAAAAGUAAUACAAGUACAAACACUAAUAAUAUUGAAUGCAAUUUAAAUUCCAUUUUAAAAUAGAUAAUAGGGUUUAAAAUAACAUGUUGAAAAUUACACUGGAAUUAGCAAAAUUUAAAAUCUUAGGAAGAAAAAUCCUAAUUUGUAUGUGAAAAUGUUUUGAACUGAGGAAAAUUAAGACUAGCAAGAGUAGAUAGGGGUUGUCUAGUAGGAAUGUUAGACCCAUCAGCCAUCUGAUUAUGCUGCGACUGAUACUAGCGUGUAGUUUUCACCCAGUAAAUUAUCAAGUGGUGCAGUAGAAAAAGCAUGGUAUGUAGAAUCAUAAGACUCAUAGUCUGGGGUCACCUCUACUACUCACUUGGCCAUGUGGUUUGGAACACAUCACAAAAGAUUUAUGAGCCUUCGCUUCUUCACAUCUAAAAUCGUGAUUAUUUUGCCAACUCCAUGGAAUUGUUUAGACUUUAGAGGAUUACAUAGGAUACAAUGGACUAGUUCCUUGAACAAGUACUUGCCCCCAAAAUGUUACCAUUUUUUCUGGUUGUGUGACUGAUUUUGCAAUCAGCAAUUUAAUAAUAAUGCAUUCAACAGGUUUAUAAUAUGCAUUCAAUGUGACUCUUGCAUAUAUCUCAUAAAAACAAAUUUGAAUAUUUUUCUCAUUUUAUCACUCACAUAUCUUUGAGAAUGGGAUCAUAGUUUUAUUUUGAUAAUGAAGUAAUAGAGUCAAUUCCUGAACAGGCUAGUUGACUUUAAUGAGAAAUACCCAUUUAUUCACUCAUUCAUUUCAUUUUCAACUCUUAAAUCCAUAAUGGCCCCUUCACUAACUGCACUAACUGGGGUUCUUAUAUUAAUAAGAUGGACCAGAUGCUUCUAUCACCUCCAAAAAAUCUUUGUAGGCAGAGCAAUAAAGAGUACUGAAUCAUUUUAAGAAGUCGCAUAGACAAUGACUUUUGACCAUGGAAGGACUGGGCUUGAUCAAGCAAAUUCUAUUUCAAAGUUUUACUUGCAAGGUUAUUUAUUACUGUGUGGAAUCUCACUCCUGUGGCUGGGGUCAAGAAAAAUGGGGACACAGGUGUCUGCCUAUUUGCACAGGCAUUAAAAAGUGUUGUAAAAUG

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