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Homo sapiens (human) long intergenic non-protein coding RNA 2728 (LINC02728) URS000075ED9D_9606

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LINC02728: LINC02728 is a long non-coding RNA (lncRNA) that is associated with prognosis in various cancers, including multiple myeloma (MM) and gastric cancer [PMC8508148] [PMC8762254] [PMC8739709] [PMC10040790]. In MM, lower expression levels of LINC02728 are associated with a shorter progression-free survival (PFS) [PMC8508148]. LINC02728 is located between the NARS2 and GAB2 genes, which are involved in IL-6-induced proliferation and survival of MM cells [PMC8508148]. In gastric cancer, LINC02728 is one of the lncRNAs used to construct a prognostic model based on ferroptosis-related lncRNAs, and its expression is higher in higher neoplasm histological grade groups [PMC8762254]. Additionally, LINC02728 has significant differences in myeloid cell lines and may serve as a predictive biomarker in these cells [PMC8739709]. In the context of acute myeloid leukemia (AML), LINC02728 is one of the lncRNAs used to construct prognostic models based on its expression levels. It is expressed at higher levels in the high-risk group of AML patients with stomach adenocarcinoma (STAD) [PMC10040790]. Overall, LINC02728 has been implicated as a prognostic marker in various cancers and may have functional roles in cancer progression.

Genome locations

Gene Ontology annotations

Sequence

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AGCCUGUGGUGGUUGCCGAAGAACUUUAAUUACAGUGUCAGAGUGUUCAGGGACAGUCCCAACUCCCUUCAUGUGAGGAUUGCAGAAAUGGGCUUGGAUCGUAUACAGACAGCGUUAUGAGGCAUUGCUGAAGAACACACAAAUCUGCCUGGAGCUGUUUCCUGAACACAGGACCAAAAGGCAGGAAUCAAAAGUAGUAAUGAGUUUAGUUAUCUGUCUGUUACUGAAGGUGACUUCUAGGGCAUCCUCCUGGCAUUGCUUCUGGAAUACAGUGACUUAGACUUAUUCGGAAGAACAUCUCUAUGCUGUUCAUCACAUCGCCAGCACCUAGCCCUGUGCCUGUGCAUAGUAAAUGCUCAGAAAAGAAAAAACAACAAAGUUUCCAGCUCUUACUCUAGAUUGACACUGGACCUUGGAGAUGCUUGCAGCCACUAAAUGUAAUGCCACAUGAUUGUUGACCCAACAAUAAUCCAGUUAAAAAACAGUCUUCAGAGUUACUACAUCAUCAGAAUUAACCCUGAUUACAUCAAAUUAUGUUGAAACAGACCACAGCUGUUUGCCCUGUUGAAGCAACUGCUUGAGAGCUCCUCCGGAAGAUACAUCUGGGUGUCACUAAGAUACAUUUUGGGUUUAGUUUUGUUUCUCAACACAAAUGUAGGAGGGAAACAAACCCUGUUCUGCUGGGGUGCCUGGUGGGAGCUGAAAACCUUGUGAUUCUCCAGCAGUCAAAAGUCAUCUCAAUUACCAAAGAGAAGGGAACCUGAGAUCUUUUGUUUCAGUUUUCUAUAGGAAGGAUGUAAGAGGAAGGAAAUUCAAAUCUGUUGAGUAUUGCUCUUGCCAGCAAAAAGAAGUGGAACUGACUAGUGAGAUGGUGGUGAGAUUUUCUUUGGUGGCUGUGUGCAGUGGUAUCAACCCAGGAGAGUAGACUGUUCAAUUGUGAAGAAUUUUGCAAGAUGGUUGUUAAAGUAGAACAUCGUUAAAAUUAAGUUGUAAUAAAAAAAGGGAAAUAAGCAUUGGAAAAGAUGUGGACAGAUUGGAACCCUCAUACAUUGCUGAUGGGAAUGUAAAAUGGUGUAGCCACUGUGGAAAAAAGGUCAGCAGUUCCUUAAAAAGUUAAACAGUGUCACCAUAUGACUCAGCAUUUUCACUCCUAGAUAAAUACGUAGAUUGAAAACGUAUGUCCACACAAAAACUUGUACAGGAAUGAUCGCAACAGCAUUAUUCAUAAUAGCCAAAAAGUGGAAACAACUGUAAUGUUCAUCAGCUGAUGAAUGGAUAAAAUGCGGUAUAUAAAGAACUGUCAAGUGCUUCAACAUGGAUGAAACUUGAAAACAUUAUACAAAGCGAAAGAGGUUAGACACACAGGUCACAUAUUGUAUGAAUAUGGUUAUGUGAAAUGUCUAGAAUUGGCAAAUCCAUAGAGAUGAAAAGUAGGUUAGCGGUUGCCAGCUGAUGGGAUUGGGGGAAUGGAGAGUUGCUAAUGGAUAUGGUGUUUCUUUUGGGGUAAUGAAAAUGUUCUGGAAUUAGAUAGCUGUGGUGGUUGUCAAAGUUGAUGAAUAUAUUAGAAACCAUGAAUUAUAAACUUUAACAUGGUGACUUUUGUGAUACGUGAAUAUCUUAAUUAAAAAUUAAGUUAUAUAAAAAAAAAAAAAAA

Taxonomic tree

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Publications