v24

Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Homo sapiens (human) long intergenic non-protein coding RNA 668 (LINC00668) URS000075E986_9606

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

LINC00668: LINC00668 is a long non-coding RNA (lncRNA) that has been extensively studied in various cancers. Immunohistochemistry analysis confirmed the relationship between LINC00668 and E2F1 in gastric cancer (GC) [PMC5029621]. LINC00668 has been found to be up-regulated in gastric cancer tissues and is an independent predictor for overall survival of gastric cancer patients [PMC6590035]. In hepatocellular carcinoma (HCC), silencing LINC00668 was shown to inhibit tumor growth, and up-regulation of YY1 counteracted the effects of LINC00668 knockdown [PMC7214398]. Additionally, two lncRNA signatures, including LINC00668, were developed to predict the prognosis of patients with relapsed HCC [PMC8438305]. In breast cancer cells, LINC00668 was found to associate with SND1 and its knockdown inhibited colony formation abilities [PMC7033544][PMC6628964]. Joint-effect analysis of LINC00668 with other genes showed better diagnostic value than individual genes alone [PMC6741837]. Furthermore, upregulation of LINC00668 was correlated with lymph node metastasis in breast cancer patients [PMC8381522]. Prognostic analysis revealed that LINC00668, along with other genes, had prognostic significance in HCC [PMC6741837]. However, the tissue specificities of LINC00668 in tumor cells were not reported in previous studies [PMC6741837]. References: - PMC5029621: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029621/ - PMC6590035: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590035/ - PMC7214398: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214398/ - PMC8438305: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438305/ - PMC7033544: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033544/ - PMC6628964: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628964/ - PMC6741837: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741837/ - PMC8381522: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381522/

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences 
GGGGCGGCCUGGGACUCGGGGGCGGGGUCAGUCAUAUAAGGCUGUGCCCAGCGCUUUUGGAAGCAGUAAGUCCAGCCCGAGGCUAAGGAGGUGUUAACCACCGAAGGGAGGUAGAAUGUUUUUCCCCACCAGAGGAGGCAGCGACCACGUCUCCUCUAUGGAGGCAUUCAAGAGCCGUCCAGCUGAAGCAGCAUCACUGUCUGAGCUCGGAAGGCACAAUCCACAUAGGUCUGCAUGGUCCACCGAGCUGCAUACCCACGGGGCCAGCGGGAGGUGGGCAGCUGCUGGGCUCUCUUCUGAAGCAGACAGGAUCUCACUCUGUUGCUGAGGCUGGAUCACAGCUCCCUGCAACCUUGAACUCUCCCUCAAGCAAUUCUCCCCACUCUGCCUUCCAAAGCACUAGCAUUAUAGGCCUAAGCCACCACUCCCAUCCACUGUAGUGUAAACUGUCUCCUUCAAUGUUUCCAAUAGUUGCGGAGCAGAUCAGAUAAGGGUUCUUCCUGUCUGUUGCUUCAAGUUUCAUUCUCUCUUUAAACAAUACAAGGUUGGCUUCCAUGGUUCCUUCUUAAAGAAUGUUGAAGGUGUGUCUUCAGAUUCAUUUAGUGUUCGUGGAACCCCAGGGAAAGCUGAUGUAAAAACCUCUUUUUUCUCCCAUAUGUCUCAAAAAGUUGUAUUUUCUGGGUCCAAGGGAUCUGCAAGCCUCCUAAAGGCAUUUCCAUUGUCACUACCACCAGGUGUGAACUGUAAUCUGGCACGUAUAGUUCCAAGAACUGUCAUAAUAGAUGCUGAAGAAACAUUGUGAAGUUAACUCGCUGUUACCAACUGUGAAGUCAUUAGCUAGAGGAAUCUUGGGCGGUCUGAAAUCUGAGAUACUGUGGAAAGAACAGAAAGAUCCUGUAUCUUUCCUAUAAUUGUUCUACUGGAAGUUGUCAUUUUACACAGGAGACAUUCUGUUUUAUUUAUUUUCUUUUGAGACAGGGUCUCACUCUGUCGCCCAGGCUGGAGUGCAGUGUUGUUACCACAGGUCACUGGUGCCUCCACUGCCUGAGGACUGCUCAAGCAAUCCUCCUGCCUCAGUCCCCUGAGGAGCUGGGGCCACAGGCCUGCACCACCAUGCCUGGCUAAUUAUUUUUAUUUGUAGAGACAAAGUCUAUCUUGCCUAGGCUGAUCUCGAACUCCUGGGCUCAAGUAAUCCUCCCGCGGUGGCUUCUCAAAGUGCUUGGGAUUACAGAUGGUCUUGCUCUGUCACCCAGUCUGGAAUGCAGUGGUGCCAUCAUAGCUCACUACAGCCUGAGCUGUACUGAGCUCGAGGGAUCUUCCCGUCUCCGCCUCCUAAGCAGCUGGGACUACAGGUAAUGGAAGUGGGCAGAGAAUGAUCCUUUCCCUAGGCUCCAGUGUGUAAGAAUUAAAGAAAGAGGAAAGAAACACAAUGGCUUGAUGGUCGAGGACAGGUUUAUUUUAAAGAAAACAAACCCAAGAGUGGCUUCUGGCUGAGUUAGAUCAGAGAAGAGAAGUGAUUUUCUUGAAAUGCAUGAGGCUGGAAAGGGAGCUGGCACUUAAAGUGGCGGUGUUUGUCCGAGAGGAUGGUGCUCCUGCUCUGUCACAGUGGGCAUGGGGAUUCAGGCCACUGCCACCGAAUUUCAAGAGCCCAAGCACAGAGCCCAGAACUAAAUUGUGAGGGUUUAAAAAAAAAAAAAGCUUUAUUGAAGUAUAAUUGACAUACAAUAAACUUGAAUAUUUAAAGUGUACAA

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

Publications