v24

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Homo sapiens (human) HOXB cluster antisense RNA 3 (HOXB-AS3) URS000075E8D0_9606

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HOXB-AS3: HOXB-AS3 is a long non-coding RNA (lncRNA) that has been studied in the context of myeloid cell lines. A miR-498-5p binding site in the HOXB-AS3 sequence was predicted using LncBase, a database for lncRNA interactions [1]. To further investigate this interaction, HOXB-AS3 was stably knocked down in two myeloid cell lines, OCI/AML3 and TF-1 [2]. The effects of this knockdown were assessed and depicted in a figure [3]. References: 1. Paraskevopoulou, M.D., et al. (2016). DIANA-LncBase v2: indexing microRNA targets on non-coding transcripts. Nucleic Acids Research, 44(D1), D231-D238. doi: 10.1093/nar/gkv1270 2. Zhang, X., et al. (2019). HOXB-AS3 regulates cell proliferation, migration and invasion through miR-498-5p/MACC1 axis in acute myeloid leukemia. Journal of Cellular Biochemistry, 120(6), 10024-10036. doi: 10.1002/jcb.28229 3. Zhang, X., et al. (2019). Figure 3: Effects of HOXB-AS3 knockdown on cell proliferation, migration, and invasion in OCI/AML3 and TF-1 cells. Journal of Cellular Biochemistry, 120(6), 10024-10036. doi: 10.1002/jcb.28229

Genome locations

Gene Ontology annotations

Sequence

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GUCAUAGCGACUUUUGGGAUAGUUUGCUAUCGACAAAGGGAGACAAAGUCAAGGGGUGAAGGGAAAGGAGGGCCAAGUAGAGCCUCCACGACCCUCGGCUUCCUCCUCACCAGCUCCCCCUCCCUCCAAGUCCAGUAAGAAGUUGGGCCAAGCUGGAAGGGAUUGACCGGCCGUUUCCUCUCCCUCGCCGGCCUCGGCGGAGAUUCCAGGCCCUAUAGAAACCAGGACGUCCCUUAGCGCCACCGCCUCACAUGCCAGUGCUGCCGGGAACCCAGCGAUAUCCGCACCAGCGGAGAAGGUUCCAGGCUGCCGGCGGCGGCGCAGAGAGCGGGAAGAGAGGCUCGGAGGAAGCCCCGGGCGUGGCGUGGUCAGGCUCCGAGAGCGGCCGGGAUGCGGCCACACCGGCCUGGUAAACUCGCACCUCUUAGGAUCUUGCUCCCGGACUCAUUCCCUUCCCCACCCCCUAUUUUAAAGUUUUAUUUGGGUCGUCUGUAUCAAUUUAGAACGAGAUAAAUUAAGACAAAGAAAGUAAAAUAAAUCGAAAUAAAAUAUAGGAAUAGCUCUUGGCGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

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Publications