v24

Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Homo sapiens (human) PTPRG antisense RNA 1 (PTPRG-AS1) URS000075E7B9_9606

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

PTPRG-AS1: PTPRG-AS1 is an up-regulated ERAR lncRNA gene that has been associated with poor prognosis and increased metastasis in osteosarcoma patients [PMC8766859]. It has also been found to be up-regulated in response to E2 treatment [PMC4991000]. The expression level of PTPRG-AS1 has been used to compare the survival of patients, with high expression levels being associated with poor prognosis [PMC8063323]. Knockout of PTPRG-AS1 has been shown to enhance the sensitivity of nasopharyngeal carcinoma (NPC) cells to X-ray radiation [PMC9066117]. PTPRG-AS1 acts as a molecular sponge for microRNA-194-3p, indirectly regulating radiosensitivity in NPC cells [PMC9917593]. Additionally, PTPRG-AS1 directly targets miR-199a-3p [PMC8645374]. The effects of radiation on the expressions of PTPRG-AS1 and miR-200c-3p have been studied in H157 and H1299 cells, with exposure to 4 Gy radiation being used as a treatment condition [PMC7672737]. PTPRG-AS1 is an up-regulated ERAR lncRNA gene that is associated with poor prognosis and increased metastasis in osteosarcoma patients. It is also up-regulated in response to E2 treatment. The expression level of PTPRG-AS1 can be used as a prognostic marker for survival. Knockout of PTPRG-AS1 enhances sensitivity to X-ray radiation in NPC cells. It indirectly regulates radiosensitivity through its interaction with microRNA molecules. Additionally, it directly targets specific microRNAs. The effects of radiation on the expressions of PTPRG AS1 and miR 200c 3p have been studied using specific cell lines and radiation doses.

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences 
GCGCGGUGACGUCACCGCAUCUUUAUAAAGGGCCGCCUUGGGGCGCGAAAAGUUCGUGAGGUGUAGUCGCGGCAACCAGGAGGUGCACCCACCACUAGAAUUUGAACAUCCUAAGAACAGGUAUUUUUGUCUCUGCUUUGCUGAUGUAUCCUCAGCAACCGGAACUGCCUGACAUGCCCAGUUCUGGUGAUGAUUUCACUUUUGACAGAAGCUGUCCCUCAAAAGCAAACAUGCAAUAGAAGAAACAGAUCUCAAUGCCAUCCAUCUGCAGUUGUGACAAGCAAAAAAGUCUCCAGACAUGGCCAAAUGUCCCCUGGGGGGCAAAAUCACCCCCAAUUGAGAACUACUGCUCUAAACUAUGGAGUCUCACUCUGUCACCCAGGAUGGAGUACAGUGGCGUGAUCUCGGCUCACUGCAAGCUCCGCCUCCUGGGUUCAUGCCAUUCUCCUGCCUUAGCCUCCCGAGUAGCUGGGACUACAGGCGCCUGCCACCACGCCCGGCUAAUUUUUGUAUUUUUAGUAGAGACAGGGUUUCACCGCAUUAGCCAGGAUGGUCUCGAUCUCCUGACCUCGUGAUCCGCCCGCCUCAGCCUCCCAAAGUGCUGGGAUUACAGGCGUGAGUCACUGUGCCCAGCCAAGUUUAGUAUUUUUUGUAGAGACAGAGUUUCACCAUGUUGGCCAGGCUGGUCUUGCACUCAUGGCCUCAAGUGAUCCACCUGCCUCGGCCUCCGAAAGUGCUGGGAUUACAGGCGUAAGCCACUGUGCCUGGCCUUAAAUGGGUAAAUUUCAUAUGGUAUAUGAAUUAUAUUUCACUAAAACUUUAAGAAAACAUUAUACAGUACUGUUCAAAUUUUAAGUGGUCCAAUUUAAAUGCACUAUUGUAUACAAUUCUAUGUAAUGUCCUUACCAUGGUAUAUGUUAACUAUAAAUAUCUAUGCCCCUACCCUUAGUAUCAAAGCAUAUAUUAUAUGCCAGUGAGCCAAGCCCCACAUGUCUGUGAAAUGUGGUCUUCUAGCCAUAGAAGUAGCUUGUGCUCCUAGGGUAUUCCUUGAGGCUCUGUAUGAAGAAUGUCCAUUUGUUUGAGUCCCUAACCUACAGAAUAUUCCUGACCAUGGAAAUGUGAUAGAUAGGAGUAAGCACAUGGACCAAAAGGCCUGGAGGCUCAUCAUUUAAGGUACAAGCCAAUUAUGUAGUCUUUGAAAGAAUGCUUUGAAAUUCAGCUUGCUUGAUUCAAUUCCCAAUAUUUUCAUUUGUAUUAAAAGAUUUGGCCCUUACAGGUUAAAAACAAUGUCAGUGUAACCAAGUGACAUUCAAAUUUUGGCUCCCAACAUGUGAUAUGACAUCACUUCAUGUGAAAAUAGCGAAGCUCCAAACAUUUUCUUUCAGUCACCUUAUUAAGCUCGCUGAGCCCUGACAGCCUAAUGAAAGGCUAAGGGGGAAGAAAAUGUCCCAACUUCUACACUGUUGAAGAUGGGCUAAUGAGAGGUUAGCUUGCAAGAAUCAUUCUUUCUUGGCAUCCUGCUUCUGACUGCUUGGCUUUCAGCUUAUACCCAGCAUGAAAAUUUAAUUUCCUCGCAGUUGAAGGUAGUUUAAAGCUUAUUACUCACAUGCUAAAAUGUUGAUGUAUCUGUUUUUGUGCUUGUUUUCUGGAUGAUUGGAAUGCUCUGCAGUGAUGUUCAUAUCAGCAGUACAGCGCUGGACUUCCUAGUGAAGAAAACAGCAAGAUUAUAGACACAGUUUAGAAACAAAGGAACACCAUAUACAUUUAAAGGCAUAAAGUAUUUACUCACUCCCUGGCCACAGCCACCGUUACCUUCUCAAUCCCAACUUCGGAUAUAAUUAUUGAUAUAUUUAUAACGAGUUUAUGAAGAAUGUGAAAAAGGUAUAAAGAUUUCAUUAUUUACUAUUUCAUCAAUCAUCUACUUUUUUCUAGUUUUUGACCUAGUCCCUGAGAUGUAAAACAAUAUCUCUUUUUGAAUACAUCAUAGUCUAUGGGUGAGAAAAAUAUUCAAAAAGAUAGUCAAACAUGAUGAAUACAAAAGAGGCCUGAGAAAGCUCUGAUGGGAGCACAGAACAGAGGAAGGCUUUAGACAGGUGAAAAAAUUUACCUAAGUCUUAAAGGAAGAAAGGGAAUUUCUAAGAAGUAUAAUCUCUACCAUGAUUUGCAAUAUGCUUACAGGCCUUAUAGCCUCAUUUUAUAAUUGUGAGGGUGCAUUGACUCUAAAGACUCAGUGCUGAAAUAACCCUAAUAACAGCCCAACUAAUGGUCAUAUCUCAUAUAUACAGUCUUGACAAAUUAUUUGUGAACUCUAGUAUUUUAAAAGUUAUCCUUCUUUGGAAAAAUAGCAGUAGCAGAAAUAACACUCUUAUCCUACCUUGGCCGUGGAUUUAAACGUCAUCCAUUAGCCUAAUACAACGUUGCUGAAAAGCCAAAUUUUUCUACACUAUAUGCUUCAAACCCAAGAAAGUACUGGAGCUGACUAAUAAGGGAAGUCAUUAGCAGUACACAGCUGCUACAAAGAGCCUGAACAAAGUAACACAAAAUUAUCAGGAGAAAUGUUUUACACAGAACAGAUGUAGCAGAGUUUAGAAGCAUGCAGACUUUUUUUUUCCACAAAGGAGUUGCCUAGUAAUUAUGCAUGUUUUCCAUAGUAUUUACAUUAAACAUAAUGAAAACAAUGAAAAAAAAAA

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

Publications