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Homo sapiens (human) long intergenic non-protein coding RNA 1551 (LINC01551) URS000075E7AC_9606

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LINC01551: LINC01551 is a long non-coding RNA (lncRNA) that has been implicated in various biological processes and diseases [PMC7564449]. In a study on patients with IDH mutations in oligodendroglioma (OD), the expression levels of lncRNA INHBA-AS1 and LINC01551 were found to be associated with different survival outcomes [PMC7564449]. LINC01551 was also found to be part of a ceRNA network involving hsa-miR-301a-3p, which classified subgroups of OD and lower-grade glioma [PMC7564449]. Interestingly, the survival pattern of LINC01551 and INHBA-AS1 related to this miRNA was different in astrocytoma [PMC7564449]. Although previous reports suggested a tumorigenic role for LINC01551, the study on OD with IDH mutations showed clinically positive results for its involvement in the ceRNA network [PMC7564449]. Furthermore, gene expression analysis showed that the expression pattern of LINC01551 in OD was more similar to that of normal brain tissue compared to other subtypes of lower-grade glioma [PMC7564449]. In other studies, LINC01551 has been implicated in hepatocellular carcinoma metastasis and its regulation by miR-132-5p in nasopharyngeal carcinoma [PMC9467814] [PMC8685624]. In addition, LINC01551 has been identified as one of the differentially expressed lncRNAs associated with ventricular septal defect (VSD) and has shown potential as a therapeutic target for limiting cell invasion abilities and proliferation in VSD [PMC9979828] [PMC8682977]. Overall, these studies highlight the diverse roles of LINC01551 in various diseases and biological processes. Further research is needed to fully understand its mechanisms of action and potential therapeutic applications.

Genome locations

Gene Ontology annotations

Sequence

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GGGUUGCUGGGGUUGUGUAACUGUGCCUAGAGGGCGGGGUUCCUGUACAUUCCUACUUCACCAGAUAACCUGCCCCCAACACCACUUCAGCUUCUGCCAGACAGAUGGAACUCUCCAGCAUGAAAAUCUGCGCAGCCAUUCCAACAAGCAGGGCUCUGCCUGAGGUUGUCCGAAGGAUGCCGAGGAAAAGGAUAUCAGGACUGGAAUGGCUCUUACAGCAAGAUCCAGGUUUUUCAUUAGUCAAUACAGUGAAGGCUGGCAUGAUCAUCAGCUUCCCAUCCAAUAAUAUCUACUCAUCAGUGUGCUGUUGUCAAUCAGAGAUUUUCAAGUAUGAGUUCUCCAACUCAAAGAAAAGUAGCUGGAUCCAGGAAGAAAGGCAUUUGGGGAAGAACAACGUUCUUUACAGUGCUCAUGAUGUGUCUCCAGAGAAAGUUACUUCAGCACUAAAAAAAACAAACAAACAAACAACAACAAUAAACAACUUUCCUCUACAGUAUCUUCCAGGGUCUAAACUAUUAGACAGGUUCCUAAGUUUAUCCAGAUCUCUCCUAUGUCUGAAUUCUUGGUCAUCUUCCUUGCCUCUGGCUCCACAGGUAAAGAAGAAAUAAUAAUAAAGGAACAAAAAUUAUAUGUUUCAGGCCGGGCGCGGUGGCUCACGCCUGUAAUCCCAGCACUUUGGGAGGCCGAGGCGGGUGGAUCAUGAGGUCAGGAGAUCGAGACCAUCCUGGCUAACAAGGUGAAACCCCGUCUCUACUAAAAAUACAAAAAAUUAGCCGGGCGCGGUGGCGGGCGCCUGUAGUCCCAGCUACUCGGGAGGCUGAGGCAGGAGAAUGGCGUGAACCCGGGAAGCGGAGCUUGCAGUGAGCCGAGAUUGCGCCACUGCAGUCCGCAGUCCGGCCUGGGCGACAGAGCGAGACUCCGUCUCAAAAAAAAAAAAAAAAAAAAUUAUAUGUUUCUGUCGGGCUGACUCAUUCCACUUUUGAAGCACCCAGUGGAUUAAUUAGUCUUAUUAUUGCAUUUACUGUCACCUACACAUUUGUUUGUGGGAAGGCACUCCUCUUGGCAUUUGCUUAGUUGGAAAAAGGAACACUAAGACUAUAGCCACUGGAUAAUGUUCUUGAAGUUCACGGCACUGUGGCAGCAUAAAGCUUGAACAGACCUAGUUUUUUUAUUGAUGGAGUGCAACUGAUGUAGCACCACUUUUCUCUGACACUGUAUAUUAGCUUUUAGUUAUGAACUACUUCCUUCCAGUGCAGCAGUUGUUGCCUACCAUUGGUACCAGUUUGGCACCAUUAUAAAGAAACAUUGUACCUCUUAUAGGAAGAAUUUGGAGAGUUUUGGUAUGGUAAUCAAGAUGUGUAUUGUAAUAAUUAACUGAAUUCUGUGAACACACUGUUUCUACCUUAAGUGAAAGAAAAAGAGAACAGCUGCAAUUAUUUAUCUUCACUCAUUUCUCAUAGAUAGCCAGGAUUUUUCAGUGUACAUUCUCUUGUCCUGAAAUUAUUUUCAGUUCUUGUUGAUUCUUAUAGAUUAUAAUGAGAAAGGCACGAGCAAGAAAUUUGAAAUAAAGAACACAAAAUGAGAUUGCCCUUUGGUUGUUAAAAUUGCAGAUUUAACAAAAUAGAUCAGCAAAAUAUGUGCAAAGUUAUCUUAACAGAUUAAUUCCUAUCCAGCAGGCUUUAACAAAAACUAAUAGAAGCUAUUACAUAUUUACAGAAAAAAAAAUUUAGCCAUGAAAGCUACUAAAGAAAAGCCAGAAACAGCGUAAGAAUUCCCUACUCAAAUAUGAUUCAGAGACGAGGGUGGGGACUUUAUUCCACUGGACUUCAGUCCCAGUGACAAGGCCACUACUAUUGUGAAUUAAUAUCAGGCUAAUUAAACUUGAUGUUAUUAAAUGUUCUAUCCAUAAAAUUUUUCAUUCAGAAUUCUUGUUUUUCAAACAACAUUCUGGAUUAUUAUUUAGCUGUCAAAGUAGCUGUGUUCUUAGAAAAUACAUCAGUCAGGGCUGGGUACAGUGGCUCAUGUCUGUAAUCCUAGUGCUUUGGGAGGCCAAGACAGGAGGAUCACAUGAGGCCAGGAGUUUGAGACCAACUAAGUCAACAUGGUAGGACCCUGUCUCUAUCCCCCUCUACCCCCCAAAAAAUUAGUCAGACAUGGUAGCACAUGCUUGUAGUCCUAGCUACUUGGGAGGCUGAGGUGGGAGGAUCUCUUGAGCCCAAGAGUUCAAGGUAGCAGUGAGCUGAUUGCACUACUGCACUCUGGCUCAUGCAAGAUAGGAAGACCCUGUCUCAGAAAAGAUUAAAAGAAAAUAAACUAAUCACACAAAUUUCAAAUAUACUAUUUAUAAUGGUAGAAACAUUUUAGUGAGCAAUGAUCCUGGCCUUUAGUGAGGUUUUUCUCAUAACAAUUUGUCAUAAAUGAAUAAUUUCUGGGUAAAACAUUAUAAUUUCAUUUUUUCUUUAUUUAUUUAUUUUUAUUUUUAUUUUUGAAACAGAAUCUCAUUUUGUUGUCCAGGCUGGAGUGUCCGCCUCCCAGGCUCCAGUGAUCCUCCAGCCUCAGCCUCUUGAGUAGCUGGGACUACAGGCAUGCUCCACCACGCUCGGCUAAUUUUUGUAUUUUUUGUUGAGAAGGGGUUGUGCCAUGGUGUCCAGGCUUGACUUGAACUCCUGGGCUCAAACAAUCAGCCUGCUUUGGCCUCCCAAAGUGCUAGAACUACAGGCAUGAGCCAUGGAGCCCAACCUGUGAUUUCUUUGCUGUGUACCCCCAUUUGAUGGAUAAUUUUUUGGCAUGUUGAUAAACGUCAGGGUGUAAAGUAUCCAGUAUGAGGGGUAAAGCCAGGAUUAUAAUAAAUUUGUCAACUUCAGGUUUUCUUGCUAGCCUUUUCUGUGAUAUACAAAGUGCACAUACAACUACAUGGGUAGGAGAAUUGUUGAAAUAAGUUAUCAUUGUUCAAACAAUAAUUUGUUGGAACCAAAUAUCACCCACAAUGCAAUUGUCUACCUUUAAAGAAUGGCCAUAGAGUCAAAAACUUUCUUUUGAAUCCUGGAUUCACUAUUUAUUUGAUGUGAGAUCACCUUUACUUUUAUACCAUCAAUUUCCUCAGUGUAAAGAGUGUAUUAUUAAAAUUCCCUCGUACGGUCAAAAAAAAAAAAAA

Taxonomic tree

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Publications